Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns
文献类型：期刊论文
| 作者 | Xu, Tongli1,2; Cui, Yulin3 ; Qin, Song2,4; Wang, Yin-Chu2,4,5
|
| 刊名 | BMC GENOMICS
 |
| 出版日期 | 2023-11-16 |
| 卷号 | 24期号:1页码:8 |
| 关键词 | Lectin Gene family Evolution Cyanobacteria Motif |
| ISSN号 | 1471-2164 |
| DOI | 10.1186/s12864-023-09790-8 |
| 通讯作者 | Qin, Song(sqin@yic.ac.cn) ; Wang, Yin-Chu(ycwang@yic.ac.cn) |
| 英文摘要 | Lectins are glycoproteins that can bind to specific carbohydrates, and different lectin families exhibit different biological activities. They are also present in the cyanobacteria and many of them have shown excellent therapeutic effect, which deserve for bioprospecting. However, in comparison to those from terrestrial plants, the current knowledge on cyanobacterial lectins is very limited. To this end, genome-wide analyses were performed to find out their evolutionary mode and motif patterns in 316 genomes of representative taxa. In results, 196 putative cyanobacterial lectins were dig out and 105 of them were classified into known families. Seven lectins were found to be belonged to distinct two lectin families, and they may have the potential activities of both lectin families. Whereas no MFP-2, Chitin, and Nictaba family lectins were found. What's more, the Legume lectin-like lectin family was found to be the richest and most complex in cyanobacteria, which could be a main research direction for future cyanobacterial lectin bioprospecting and development. Our classification and prediction of cyanobacteria lectins is expected to provide assistance in the development of lectin-based medicine and provide solutions to the current thorny viral and tumor diseases in humans. |
| WOS关键词 | ALGA EUCHEUMA-SERRA ; BINDING |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Genetics & Heredity |
| 语种 | 英语 |
| WOS记录号 | WOS:001103440800002 |
| 资助机构 | Not applicable. |
| 源URL | [http://ir.yic.ac.cn/handle/133337/36624]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 通讯作者 | Qin, Song; Wang, Yin-Chu |
| 作者单位 | 1.Shandong Univ Tradit Chinese Med, Jinan 250335, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 3.Binzhou Med Univ, Yantai 264003, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 5.Natl Basic Sci Data Ctr, Beijing 100190, Peoples R China |
| 推荐引用方式 GB/T 7714 | Xu, Tongli,Cui, Yulin,Qin, Song,et al. Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns[J]. BMC GENOMICS,2023,24(1):8. |
| APA | Xu, Tongli,Cui, Yulin,Qin, Song,&Wang, Yin-Chu.(2023).Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns.BMC GENOMICS,24(1),8. |
| MLA | Xu, Tongli,et al."Genome-wide analysis of lectins in cyanobacteria: from evolutionary mode to motif patterns".BMC GENOMICS 24.1(2023):8. |
入库方式： OAI收割
来源：烟台海岸带研究所
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