New ophiobolin sesterterpenoid and drimane sesquiterpenoids from a marine-alga-derived fungus Aspergillus sp.
文献类型：期刊论文
| 作者 | Fang, Sheng-Tao ; Shi, Zhen-Zhen; Song, Yin-Ping; Yin, Xiu-Li; Ji, Nai-Yun
|
| 刊名 | FITOTERAPIA
 |
| 出版日期 | 2023-10-01 |
| 卷号 | 170页码:6 |
| 关键词 | Marine fungus Aspergillus Ophiobolin sesterterpenoid Drimane sesquiterpenoid Anti-microalgal activity |
| ISSN号 | 0367-326X |
| DOI | 10.1016/j.fitote.2023.105659 |
| 通讯作者 | Ji, Nai-Yun(nyji@yic.ac.cn) |
| 英文摘要 | Further investigation of secondary metabolites of a marine-alga-derived fungus Aspergillus sp. RR-YLW-12 led to isolate one new ophiobolin-type sesterterpenoid (1), four new drimane-type sesquiterpenoids (2-5) and one natural occurring compound (6), together with seven known compounds (7-13). Their structures and stereo chemistry were elucidated by extensive spectroscopic analysis of NMR and HRMS experiments, and by comparison with the literature data. All isolates were evaluated for growth inhibition of five marine harmful microalgae. The new compounds exhibited significant to moderate inhibitory effects towards all tested micro algae species with IC50 values ranging from 5.8 to 54.5 & mu;g/mL. |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001072059600001 |
| 资助机构 | Promotion Association of the CAS ; Taishan Scholar Project Special Funding |
| 源URL | [http://ir.yic.ac.cn/handle/133337/36718]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Ji, Nai-Yun |
| 作者单位 | Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Fang, Sheng-Tao,Shi, Zhen-Zhen,Song, Yin-Ping,et al. New ophiobolin sesterterpenoid and drimane sesquiterpenoids from a marine-alga-derived fungus Aspergillus sp.[J]. FITOTERAPIA,2023,170:6. |
| APA | Fang, Sheng-Tao,Shi, Zhen-Zhen,Song, Yin-Ping,Yin, Xiu-Li,&Ji, Nai-Yun.(2023).New ophiobolin sesterterpenoid and drimane sesquiterpenoids from a marine-alga-derived fungus Aspergillus sp..FITOTERAPIA,170,6. |
| MLA | Fang, Sheng-Tao,et al."New ophiobolin sesterterpenoid and drimane sesquiterpenoids from a marine-alga-derived fungus Aspergillus sp.".FITOTERAPIA 170(2023):6. |
入库方式： OAI收割
来源：烟台海岸带研究所
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