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Tetrahedral DNA framework assisted rotational paper-based analytical device for differential detection of SARS-CoV-2 and influenza A H1N1 virus

文献类型：期刊论文

作者Li, Fengling1; Qi, Ji3; Ren, Zengzheng1; Hu, Xiaoli1; Chen, Yan2; Li, Bowei3; Fu, Xiuli1
刊名MICROCHEMICAL JOURNAL
出版日期2023-02-01
卷号185页码:7
关键词Tetrahedral DNA framework Paper-based analytical device SARS-CoV-2
ISSN号0026-265X
DOI10.1016/j.microc.2022.108304
通讯作者Chen, Yan(ychen0612@163.com) ; Li, Bowei(bwli@yic.ac.cn) ; Fu, Xiuli(fuxiuli@ytu.edu.cn)
英文摘要Coronavirus disease 2019 (COVID-19) and influenza A are two respiratory infectious diseases with similar clinical manifestations. Because of the complex global epidemic situation of COVID-19, the distinction and diagnosis of COVID-19 and influenza A infected persons is crucial for epidemic prevention and control. In this study, tetrahedral DNA framework (TDF) was combined with a rotational paper-based analytical device, and the color change generated by the reaction between horseradish peroxidase (HRP) and 3,3 ' 5,5 '-tetramethylbenzidine (TMB)-H2O2 was used for grayscale signal analysis by ImageJ software. The quantitative detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A H1N1 virus were realized simulta-neously. Under the optimal conditions, the paper-based analytical device showed a good linear relationship between the two viruses in the range of 10-14-10-8g/mL, and the two viruses were not affected by cross reaction. This sensor provides a convenient and reliable method for clinical rapid differentiation and diagnosis of COVID-19 and influenza A.
WOS关键词NANOSTRUCTURE ; MICROFLUIDICS ; PLATFORM
WOS研究方向Chemistry
语种英语
WOS记录号WOS:000905569200001
资助机构Qingchuang Science and Technology Program of Shandong Province in China ; National Natural Science Foundation of China ; Shandong Provincial Natural Science Foundation Key Project
源URL[http://ir.yic.ac.cn/handle/133337/37108]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Chen, Yan; Li, Bowei; Fu, Xiuli
作者单位1.Yantai Univ, Sch Chem & Chem Engn, Yantai 264005, Peoples R China
2.Shandong Agr & Engn Univ, Sch Resources & Environm Engn, Jinan 250100, Peoples R China
3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714		 Li, Fengling,Qi, Ji,Ren, Zengzheng,et al. Tetrahedral DNA framework assisted rotational paper-based analytical device for differential detection of SARS-CoV-2 and influenza A H1N1 virus[J]. MICROCHEMICAL JOURNAL,2023,185:7.
APA Li, Fengling.,Qi, Ji.,Ren, Zengzheng.,Hu, Xiaoli.,Chen, Yan.,...&Fu, Xiuli.(2023).Tetrahedral DNA framework assisted rotational paper-based analytical device for differential detection of SARS-CoV-2 and influenza A H1N1 virus.MICROCHEMICAL JOURNAL,185,7.
MLA Li, Fengling,et al."Tetrahedral DNA framework assisted rotational paper-based analytical device for differential detection of SARS-CoV-2 and influenza A H1N1 virus".MICROCHEMICAL JOURNAL 185(2023):7.

入库方式： OAI收割

来源：烟台海岸带研究所

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