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Fluorescent probes for biomolecule detection under environmental stress

文献类型：期刊论文

作者Han, Xiaoyue1,2,3; Wang, Yue2,3; Huang, Yan4; Wang, Xiaoyan4; Choo, Jaebum5; Chen, Lingxin2,4,6
刊名JOURNAL OF HAZARDOUS MATERIALS
出版日期2022-06-05
卷号431页码:40
关键词Fluorescent probe Biomolecule Environmental stress Physiological pathological processes Chemical exposure
ISSN号0304-3894
DOI10.1016/j.jhazmat.2022.128527
通讯作者Choo, Jaebum(jbchoo@cau.ac.kr) ; Chen, Lingxin(lxchen@yic.ac.cn)
英文摘要The use of fluorescent probes in visible detection has been developed over the last several decades. Biomolecules are essential in the biological processes of organisms, and their distribution and concentration are largely influenced by environmental factors. Significant advances have occurred in the applications of fluorescent probes for the detection of the dynamic localization and quantity of biomolecules during various environmental stress-induced physiological and pathological processes. Herein, we summarize representative examples of small molecule-based fluorescent probes that provide bimolecular information when the organism is under environ -mental stress. The discussion includes strategies for the design of smart small-molecule fluorescent probes, in addition to their applications in biomolecule imaging under environmental stresses, such as hypoxia, ischemia-reperfusion, hyperthermia/hypothermia, organic/inorganic chemical exposure, oxidative/reductive stress, high glucose stimulation, and drug treatment-induced toxicity. We believe that comprehensive insight into the beneficial applications of fluorescent probes in biomolecule detection under environmental stress should enable the further development and effective application of fluorescent probes in the biochemical and biomedical fields.
WOS关键词HIGHLY SELECTIVE DETECTION ; INDUCED LIVER-INJURY ; CYTOCHROME-P450 REDUCTASE DETECTION ; DRUG-INDUCED HEPATOTOXICITY ; ENDOGENOUS CARBON-MONOXIDE ; TURN-ON PROBE ; LIVING CELLS ; OXIDATIVE STRESS ; IN-VIVO ; ENDOPLASMIC-RETICULUM
WOS研究方向Engineering ; Environmental Sciences & Ecology
语种英语
WOS记录号WOS:000765062500002
资助机构National Natural Science Foundation of China, China ; Science and Technology Innovation Development Plan of Yantai of China, China ; National Research Foundation of Korea, Korea ; Taishan Scholar Project Special Funding, China
源URL[http://ir.yic.ac.cn/handle/133337/37727]  
专题烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室
烟台海岸带研究所_山东省海岸带环境工程技术研究中心
通讯作者Choo, Jaebum; Chen, Lingxin
作者单位1.Univ Oxford, Present Ludwig Inst Canc Res, Nuffield Dept Clin Med, Oxford, England
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Binzhou Med Univ, Sch Pharm, Yantai 264003, Peoples R China
5.Chung Ang Univ, Dept Chem, Seoul 06974, South Korea
6.Chinese Acad Sci, Ctr Ocean Megasci, Qingdao 266071, Peoples R China
推荐引用方式
GB/T 7714		 Han, Xiaoyue,Wang, Yue,Huang, Yan,et al. Fluorescent probes for biomolecule detection under environmental stress[J]. JOURNAL OF HAZARDOUS MATERIALS,2022,431:40.
APA Han, Xiaoyue,Wang, Yue,Huang, Yan,Wang, Xiaoyan,Choo, Jaebum,&Chen, Lingxin.(2022).Fluorescent probes for biomolecule detection under environmental stress.JOURNAL OF HAZARDOUS MATERIALS,431,40.
MLA Han, Xiaoyue,et al."Fluorescent probes for biomolecule detection under environmental stress".JOURNAL OF HAZARDOUS MATERIALS 431(2022):40.

入库方式： OAI收割

来源：烟台海岸带研究所

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