Synthesis, Characterization, and the Antioxidant Activity of Phenolic Acid Chitooligosaccharide Derivatives
文献类型：期刊论文
| 作者 | Sun, Yan1,3; Ji, Xia2; Cui, Jingmin1,3; Mi, Yingqi1,3; Zhang, Jingjing1,3; Guo, Zhanyong1,3
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| 刊名 | MARINE DRUGS
 |
| 出版日期 | 2022-08-01 |
| 卷号 | 20期号:8页码:16 |
| 关键词 | chitooligosaccharide derivatives phenolic acid antioxidant activity |
| DOI | 10.3390/md20080489 |
| 英文摘要 | A series of phenolic acid chitooligosaccharide (COS) derivatives synthesized by two mild and green methods were illuminated in this paper. Seven phenolic acids were selected to combine two kinds of COS derivatives: the phenolic acid chitooligosaccharide salt derivatives and the phenolic-acid-acylated chitooligosaccharide derivatives. The structures of the derivatives were characterized by FT-IR and H-1 NMR spectra. The antioxidant experiment results in vitro (including DPPH-radical scavenging activity, superoxide-radical scavenging activity, hydroxyl-radical scavenging ability, and reducing power) demonstrated that the derivatives exhibited significantly enhanced antioxidant activity compared to COS. Moreover, the study showed that the phenolic acid chitooligosaccharide salts had stronger antioxidant activity than phenolic-acid-acylated chitooligosaccharide. The cytotoxicity assay of L929 cells in vitro indicated that the derivatives had low cytotoxicity and good biocompatibility. In conclusion, this study provides a possible synthetic method for developing novel and nontoxic antioxidant agents which can be used in the food and cosmetics industry. |
| WOS关键词 | FUNCTIONALIZED CHITOSAN DERIVATIVES ; FREE-RADICALS ; FLAVONOIDS ; HEALTH |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:000845534400001 |
| 源URL | [http://ir.yic.ac.cn/handle/133337/37407]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Ji, Xia; Guo, Zhanyong |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Qilu Med Univ, Sch Pharm, Zibo 255300, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China |
| 推荐引用方式 GB/T 7714 | Sun, Yan,Ji, Xia,Cui, Jingmin,et al. Synthesis, Characterization, and the Antioxidant Activity of Phenolic Acid Chitooligosaccharide Derivatives[J]. MARINE DRUGS,2022,20(8):16. |
| APA | Sun, Yan,Ji, Xia,Cui, Jingmin,Mi, Yingqi,Zhang, Jingjing,&Guo, Zhanyong.(2022).Synthesis, Characterization, and the Antioxidant Activity of Phenolic Acid Chitooligosaccharide Derivatives.MARINE DRUGS,20(8),16. |
| MLA | Sun, Yan,et al."Synthesis, Characterization, and the Antioxidant Activity of Phenolic Acid Chitooligosaccharide Derivatives".MARINE DRUGS 20.8(2022):16. |
入库方式： OAI收割
来源：烟台海岸带研究所
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