Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats
文献类型：期刊论文
| 作者 | Lv, Kangning1,3; Wang, Lei1 ; He, Xiaoli1,2; Li, Wenjun1; Han, Lei2; Qin, Song1
|
| 刊名 | FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
 |
| 出版日期 | 2022-02-14 |
| 卷号 | 9页码:10 |
| 关键词 | tilapia skin acellular dermal matrix collagen wound repair |
| ISSN号 | 2296-4185 |
| DOI | 10.3389/fbioe.2021.792344 |
| 通讯作者 | Qin, Song(sqin@yic.ac.cn) |
| 英文摘要 | Extracellular matrix (ECM) material with good biological activity is essential to simulate cell growth microenvironment, induce cell infiltration and angiogenesis, and promote the repair of large area acute skin wound. In this study, tilapia skin acellular dermal matrix (TADM) was prepared to simulate ECM microenvironment, which can promote substantial area acute wound healing in rats. The main component of TADM is type I collagen, which has good physical and chemical properties, biological activity and cell adhesion. TADM is a form of biomaterial with low immunogenicity, low risk of prion infection and lower economic cost than other related materials such as mammalian collagen biomaterials. Our results show that TADM can guide cell infiltration, angiogenesis, regulate the expression and secretion of inflammatory and skin repair correlated factors to promote tissue healing. |
| WOS关键词 | ARTIFICIAL SKIN ; COLLAGEN ; CARBODIIMIDE ; GRAFTS ; BURNS |
| WOS研究方向 | Biotechnology & Applied Microbiology ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:000761695500001 |
| 资助机构 | Department of Science and Technology of Shandong Province |
| 源URL | [http://ir.yic.ac.cn/handle/133337/37641]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 烟台海岸带研究所_海岸带生物学与生物资源利用所重点实验室 |
| 通讯作者 | Qin, Song |
| 作者单位 | 1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Yantai, Peoples R China 2.Yantai Univ, Sch Life Sci, Yantai, Peoples R China 3.Yantai Univ, Sch Ocean, Yantai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Lv, Kangning,Wang, Lei,He, Xiaoli,et al. Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats[J]. FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,2022,9:10. |
| APA | Lv, Kangning,Wang, Lei,He, Xiaoli,Li, Wenjun,Han, Lei,&Qin, Song.(2022).Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats.FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY,9,10. |
| MLA | Lv, Kangning,et al."Application of Tilapia Skin Acellular Dermal Matrix to Induce Acute Skin Wound Repair in Rats".FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 9(2022):10. |
入库方式： OAI收割
来源：烟台海岸带研究所
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