The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts
文献类型：期刊论文
| 作者 | Mi, Yingqi1,3,4; Chen, Yuan2; Tan, Wenqiang3,4 ; Zhang, Jingjing3,4; Li, Qing3,4; Guo, Zhanyong1,3,4
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| 刊名 | CARBOHYDRATE POLYMERS
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| 出版日期 | 2022-02-15 |
| 卷号 | 278页码:11 |
| 关键词 | Chitosan quaternary ammonium salts Bioactive anions Schiff base Antifungal activity Antioxidant activity |
| ISSN号 | 0144-8617 |
| DOI | 10.1016/j.carbpol.2021.118970 |
| 通讯作者 | Guo, Zhanyong(zhanyongguo@hotmail.com) |
| 英文摘要 | In this study, to investigate the influence of glyoxylate bearing Schiff base on bioactivity to chitosan quaternary ammonium salts, different chitosan derivatives were synthesized by ion exchange of glyoxylate bearing Schiff base with chitosan quaternary ammonium salts (TMCI and HACC). For this purpose, glyoxylate was prepared by Schiff base reaction of glyoxylic acid and amino heterocycles and it was further ionization to substitute iodide ions and chloride ions. After structural characterization by FTIR and H-1 NMR, the antifungal and antioxidant activities were measured. Results indicated that glyoxylate bearing Schiff base could improve the bioactivity of TMCI and HACC obviously. Specifically, anionic TMCI with Schiff base of amino pyridines possessed best antioxidant activity >92.40% at 1.6 mg/mL against DPPH radicals. Meanwhile, they showed antifungal activity >84.88% at 1.0 mg/mL against G. cingulate. Furthermore, the cytotoxicity was evaluated, and all samples showed good cell viability >80.14% at 1000 mu g/mL. |
| WOS关键词 | DERIVATIVES ; PROPERTY ; DESIGN |
| WOS研究方向 | Chemistry ; Polymer Science |
| 语种 | 英语 |
| WOS记录号 | WOS:000760920900008 |
| 资助机构 | National Key Research and Development Program of China ; Youth Innovation Promotion Association CAS ; 2020 Annual Special Research Assistant Project of Chinese Academy of Sciences |
| 源URL | [http://ir.yic.ac.cn/handle/133337/37651]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Guo, Zhanyong |
| 作者单位 | 1.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 2.Ludong Univ, Sch Chem & Mat Sci, Yantai 264025, Peoples R China 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Key Lab Coastal Biol & Bioresource Utilizat, Yantai 264003, Peoples R China 4.Chinese Acad Sci, Ctr Ocean Megasci, 7 Nanhai Rd, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Mi, Yingqi,Chen, Yuan,Tan, Wenqiang,et al. The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts[J]. CARBOHYDRATE POLYMERS,2022,278:11. |
| APA | Mi, Yingqi,Chen, Yuan,Tan, Wenqiang,Zhang, Jingjing,Li, Qing,&Guo, Zhanyong.(2022).The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts.CARBOHYDRATE POLYMERS,278,11. |
| MLA | Mi, Yingqi,et al."The influence of bioactive glyoxylate bearing Schiff base on antifungal and antioxidant activities to chitosan quaternary ammonium salts".CARBOHYDRATE POLYMERS 278(2022):11. |
入库方式： OAI收割
来源：烟台海岸带研究所
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