The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus
文献类型：期刊论文
| 作者 | Hu, Yuanyuan3,4; Zhao, Jingjie2; Jin, Yuening3,4 ; Du, Yi2; Zhao, Qian2; Xu, Shuai2; Li, Li2; Zhou, Yuan1,3,4
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| 刊名 | BRAIN IMAGING AND BEHAVIOR
 |
| 出版日期 | 2024-10-17 |
| 页码 | 9 |
| 关键词 | Globus Pharyngeus Resting-state functional magnetic resonance imaging Functional connectivity Thalamus |
| ISSN号 | 1931-7557 |
| DOI | 10.1007/s11682-024-00940-4 |
| 通讯作者 | Zhou, Yuan(zhouyuan@psych.ac.cn) |
| 英文摘要 | Globus Pharyngeus (GP) is a somatic symptom that accompanies mood distress. Although the etiology of GP remains unclear, its specific symptom of a false lump sensation in the throat without physical obstruction raises the possibility of alterations in brain networks responsible for somatosensory and emotion processing in patients with GP. To address this possibility, we investigated resting-state functional connectivity (rsFC) in 31 patients with GP and 24 healthy individuals using resting-state functional magnetic resonance imaging. Considering its significance in somatosensory and emotional functions, we focused on rsFC in the subregions of the thalamus. We found significantly decreased rsFC between the right caudal temporal thalamus (rcTtha) and the midcingulate cortex (MCC) as well as significantly decreased rsFC between the right rostral temporal thalamus (rrTtha) and the left cerebellum in the patients with GP. Additionally, within the patient group, the abnormalities in rsFC between the rcTtha and the MCC were correlated with the severity of somatization symptoms but not with depression and anxiety. These findings suggest alterations in the rsFC of thalamic subregions in patients with GP, shedding light on the pathogenesis of GP and potentially leading to improved diagnosis and treatment approaches for the condition. |
| 收录类别 | SCI |
| WOS关键词 | CINGULATE CORTEX ; ANXIETY DISORDER ; PAIN ; DEPRESSION ; ETIOLOGY ; CYTOARCHITECTURE ; SEVERITY ; VALIDITY |
| 资助项目 | National Natural Science Foundation of China[82004109] ; National Natural Science Foundation of China[81673737] ; National Natural Science Foundation of China |
| WOS研究方向 | Neurosciences & Neurology |
| 语种 | 英语 |
| WOS记录号 | WOS:001334460400001 |
| 出版者 | SPRINGER |
| 资助机构 | National Natural Science Foundation of China ; National Natural Science Foundation of China |
| 源URL | [http://ir.psych.ac.cn/handle/311026/49121]  |
| 专题 | 心理研究所_中国科学院行为科学重点实验室 |
| 通讯作者 | Zhou, Yuan |
| 作者单位 | 1.Capital Med Univ, Beijing Anding Hosp, Natl Clin Res Ctr Mental Disorders, Beijing Key Lab Mental Disorders, Beijing, Peoples R China 2.Capital Med Univ, Beijing Friendship Hosp, Dept Tradit Chinese Med, Beijing 100050, Peoples R China 3.Univ Chinese Acad Sci, Dept Psychol, Beijing 100049, Peoples R China 4.Chinese Acad Sci, Inst Psychol, CAS Key Lab Behav Sci, 16 Lincui Rd, Beijing 100101, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Yuanyuan,Zhao, Jingjie,Jin, Yuening,et al. The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus[J]. BRAIN IMAGING AND BEHAVIOR,2024:9. |
| APA | Hu, Yuanyuan.,Zhao, Jingjie.,Jin, Yuening.,Du, Yi.,Zhao, Qian.,...&Zhou, Yuan.(2024).The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus.BRAIN IMAGING AND BEHAVIOR,9. |
| MLA | Hu, Yuanyuan,et al."The altered resting-state functional connectivity of thalamic subregions in patients with globus pharyngeus".BRAIN IMAGING AND BEHAVIOR (2024):9. |
入库方式： OAI收割
来源：心理研究所
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