Large-scale metagenomic assembly provide new insights into the genetic evolution of gut microbiomes in plateau ungulates
文献类型：期刊论文
| 作者 | Xu, Bo; Song, Pengfei; Jiang, Feng; Cai, Zhenyuan ; Gu, Haifeng; Gao, Hongmei; Li, Bin; Liang, Chengbo; Qin, Wen; Zhang, Jingjie
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| 刊名 | NPJ BIOFILMS AND MICROBIOMES
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| 出版日期 | 2024 |
| 卷号 | 10期号:1 |
| 英文摘要 | Trillions of microbes colonize the ungulate gastrointestinal tract, playing a pivotal role in enhancing host nutrient utilization by breaking down cellulose and hemicellulose present in plants. Here, through large-scale metagenomic assembly, we established a catalog of 131,416 metagenome-assembled genomes (MAGs) and 11,175 high-quality species-level genome bins (SGBs) from 17 species of ungulates in China. Our study revealed the convergent evolution of high relative abundances of carbohydrate-active enzymes (CAZymes) in the gut microbiomes of plateau-dwelling ungulates. Notably, two significant factors contribute to this phenotype: structural variations in their gut microbiome genomes, which contain more CAZymes, and the presence of novel gut microbiota species, particularly those in the genus Cryptobacteroides, which are undergoing independent rapid evolution and speciation and have higher gene densities of CAZymes. Furthermore, these enrichment CAZymes in the gut microbiomes are highly enrichment in known metabolic pathways for short-chain fatty acid (SCFA) production. Our findings not only provide a valuable genomic resource for understanding the gut microbiomes of ungulates but also offer fresh insights into the interaction between gut microbiomes and their hosts, as well as the co-adaptation of hosts and their gut microbiomes to their environments. |
| 源URL | [http://210.75.249.4/handle/363003/61911]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Xu, Bo,Song, Pengfei,Jiang, Feng,et al. Large-scale metagenomic assembly provide new insights into the genetic evolution of gut microbiomes in plateau ungulates[J]. NPJ BIOFILMS AND MICROBIOMES,2024,10(1). |
| APA | Xu, Bo.,Song, Pengfei.,Jiang, Feng.,Cai, Zhenyuan.,Gu, Haifeng.,...&Zhang, Tongzuo.(2024).Large-scale metagenomic assembly provide new insights into the genetic evolution of gut microbiomes in plateau ungulates.NPJ BIOFILMS AND MICROBIOMES,10(1). |
| MLA | Xu, Bo,et al."Large-scale metagenomic assembly provide new insights into the genetic evolution of gut microbiomes in plateau ungulates".NPJ BIOFILMS AND MICROBIOMES 10.1(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
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