Bidirectional Win-Win: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium
文献类型：期刊论文
| 作者 | Li, Yuechun; Zhang, Wenrui; Wang, Ziqi; Cui, Zhaowen; Shi, Longhua; Bu, Tong; Sun, Jing; Cheng, Jie; Yang, Qingyu; Wang, Jianlong |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2024 |
| 卷号 | 96期号:45 |
| 英文摘要 | The lack of nanoprobes with an efficient signal response and overlook of cooperation between nanoprobes can be responsible for the unsatisfactory analytical performance of immunochromatographic strips (ITSs). Herein, asymmetrical nanobowl-confined innumerable gold nanoparticles (AuNPs) (AuNPs@AFRNBs) to enhance the light absorption are developed for quenching the fluorescence of aggregation-induced emissive (AIE) nanosilicons, which is used for the construction of a bidirectional complementary-enhanced ITS (BC-ITS) to ultrasensitively detect Salmonella typhimurium (S. typhimurium). Briefly, density functional theory-screened AIEgens with highly fluorescent brightness are confined in nanosilicons, and the nanoconfinement has improved the fluorescent brightness by 6.78-fold compared to the free AIEgens. Moreover, the substituent group effect has also enhanced the fluorescence of the prepared fluorescent nanosilicon by 10,000-fold in ITSs. By virtue of the superior light absorption of AuNPs@AFRNBs, the BC-ITS exhibits a bidirectional win-win performance for the sensitive monitoring of S. typhimurium: a turn-on mode with a high-brightness colorimetric response and an inverse turn-off fluorescence response, whose limits of detection are 364 and 302 CFU mL-1, respectively, which is approximately 100-fold more sensitive than the traditional AuNPs-ITS. Furthermore, the BC-ITS can be successfully used to identify S. typhimurium in milk, illustrating the superiority of the developed BC-ITS in point-of-care diagnosis. |
| 源URL | [http://210.75.249.4/handle/363003/61915]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Li, Yuechun,Zhang, Wenrui,Wang, Ziqi,et al. Bidirectional Win-Win: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium[J]. ANALYTICAL CHEMISTRY,2024,96(45). |
| APA | Li, Yuechun.,Zhang, Wenrui.,Wang, Ziqi.,Cui, Zhaowen.,Shi, Longhua.,...&Wang, Jianlong.(2024).Bidirectional Win-Win: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium.ANALYTICAL CHEMISTRY,96(45). |
| MLA | Li, Yuechun,et al."Bidirectional Win-Win: Asymmetrical Nanobowl-Coupled Aggregation-Induced Emissive Nanosilicon-Enhanced Immunochromatographic Strips for the Ultrasensitive Detection of Salmonella typhimurium".ANALYTICAL CHEMISTRY 96.45(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
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