Evaluation of the Multidimensional Enhanced Lateral Flow Immunoassay in Point-of-Care Nanosensors
文献类型：期刊论文
| 作者 | Liu, Sijie; Liao, Yangjun; Shu, Rui; Sun, Jing; Zhang, Daohong; Zhang, Wentao; Wang, Jianlong |
| 刊名 | ACS NANO
 |
| 出版日期 | 2024 |
| 卷号 | 18期号:40 |
| 英文摘要 | Point-of-care (POC) nanosensors with high screening efficiency show promise for user-friendly manipulation in the ever-increasing on-site analysis demand for illness diagnosis, environmental monitoring, and food safety. Currently, inspired by the merits of integrating advanced nanomaterials, molecular biology, machine learning, and artificial intelligence, lateral flow immunoassay (LFIA)-based POC nanosensors have been devoted to satisfying the commercial demands in terms of sensitivity, specificity, and practicality. Herein, we examine the use of multidimensional enhanced LFIA in various fields over the past two decades, focusing on introducing advanced nanomaterials to improve the acquisition capability of small order of magnitude targets through engineering transformations and emphasizing interdomain fusion to collaboratively address the inherent challenges in current commercial applications, such as multiplexing, development of detectors for quantitative analysis, more practical on-site monitoring, and sensitivity enhancement. Specifically, this comprehensive review encompasses the latest advances in comprehending LFIA with an alternative signal transduction pattern, aiming to achieve rapid, ultrasensitive, and sample-to-answer available options with progressive applications for POC nanosensors. In summary, through the cross-collaboration development of disciplines, LFIA has the potential to break the barriers toward commercialization and achieve laboratory-level POC nanosensors, thus leading to the emergence of the next generation of LFIA. |
| 源URL | [http://210.75.249.4/handle/363003/61948]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Liu, Sijie,Liao, Yangjun,Shu, Rui,et al. Evaluation of the Multidimensional Enhanced Lateral Flow Immunoassay in Point-of-Care Nanosensors[J]. ACS NANO,2024,18(40). |
| APA | Liu, Sijie.,Liao, Yangjun.,Shu, Rui.,Sun, Jing.,Zhang, Daohong.,...&Wang, Jianlong.(2024).Evaluation of the Multidimensional Enhanced Lateral Flow Immunoassay in Point-of-Care Nanosensors.ACS NANO,18(40). |
| MLA | Liu, Sijie,et al."Evaluation of the Multidimensional Enhanced Lateral Flow Immunoassay in Point-of-Care Nanosensors".ACS NANO 18.40(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
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