Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis
文献类型：期刊论文
| 作者 | Liu, Ying-Ying; Dou, Gai-Jie; Xiao, Yuan-Can; Chen, Xiao-Yi; Wei, Li-Xin ; Zhou, Wen-Bin
|
| 刊名 | JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH
 |
| 出版日期 | 2024 |
| 英文摘要 | This study aimed to investigate the effects of wild Cordyceps sinensis on chronic obstructive pulmonary disease (COPD) rats through metabolomics approach, combined with biochemical parameters evaluations. Consequently, C. sinensis exhibited regulatory effects on the lung's metabolic profiles in COPD rats. Treatment with C. sinensis potentially modulated glycerophospholipid metabolism, glutathione metabolism, and tryptophan metabolism, thereby alleviating oxidative stress (by decreasing MDA and GSSG, while increasing SOD and GSH) and inflammatory response (by inhibiting TNF-alpha, IL-8, and MMP-9) in COPD rats while improving lung tissue damage. |
| 源URL | [http://210.75.249.4/handle/363003/61952]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Liu, Ying-Ying,Dou, Gai-Jie,Xiao, Yuan-Can,et al. Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis[J]. JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,2024. |
| APA | Liu, Ying-Ying,Dou, Gai-Jie,Xiao, Yuan-Can,Chen, Xiao-Yi,Wei, Li-Xin,&Zhou, Wen-Bin.(2024).Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis.JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH. |
| MLA | Liu, Ying-Ying,et al."Therapeutic potential of Cordyceps sinensis targeting oxidative stress and inflammatory response in the treatment of COPD rats: insights from metabolomics analysis".JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2024). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。