Seasonal piRNA Expression Profile Changes in the Testes of Plateau Zokor (Eospalax baileyi)
文献类型：期刊论文
| 作者 | Cai, Zhiyuan; Yao, Baohui; Tan, Yuchen; Liu, Yongjie; Su, Junhu |
| 刊名 | ANIMALS
 |
| 出版日期 | 2024 |
| 卷号 | 14期号:17 |
| 英文摘要 | Simple Summary: Seasonal reproduction is a survival strategy employed by many animals, reflecting their adaptation to environmental conditions. This study highlights the differential expression of piRNAs during the reproductive cycle in the testes of plateau zokors (Eospalax baileyi) and the associated mRNA enrichment functions and pathways. Our findings demonstrate that piRNAs regulate the PIWI gene family in these high-altitude rodents, thereby influencing testicular development and contributing to seasonal reproduction. The enriched pathways of associated mRNAs regulate and activate testicular development, initiating functions crucial for sperm motility. We believe this study provides valuable insights into the initiation of seasonal reproduction and the underlying regulatory mechanisms in free-living, subterranean rodents. Seasonal reproduction is a mammalian behavior that has developed over an extended evolutionary period and requires animals to respond to external environmental changes to facilitate reproduction. In this study, we investigated the role of PIWI-interacting RNA (piRNA) in the seasonal reproduction of plateau zokors (Eospalax baileyi). piRNA expression profiles in plateau zokor testes during both breeding and non-breeding seasons were examined. The piRNAs had a distinctive ping-pong signature and ranged from 27 to 32 nt with a peak at 30 nt. Testicular piRNAs predominantly aligned to specific genomic regions, including repeat and gene regions. Analysis of the piRNA-mRNA interaction network and functional enrichment of differentially expressed piRNAs targeting mRNAs revealed their association with testicular development and spermatogenesis. Significantly, PIWIL4 is an mRNA gene that interacts with piRNA and exhibits high expression levels within the testes during the non-breeding phase. This study provides a foundation to improve our understanding of piRNA regulatory mechanisms during testicular development and spermatogenesis in seasonally reproducing animals and, specifically, in the plateau zokor. |
| 源URL | [http://210.75.249.4/handle/363003/61960]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Cai, Zhiyuan,Yao, Baohui,Tan, Yuchen,et al. Seasonal piRNA Expression Profile Changes in the Testes of Plateau Zokor (Eospalax baileyi)[J]. ANIMALS,2024,14(17). |
| APA | Cai, Zhiyuan,Yao, Baohui,Tan, Yuchen,Liu, Yongjie,&Su, Junhu.(2024).Seasonal piRNA Expression Profile Changes in the Testes of Plateau Zokor (Eospalax baileyi).ANIMALS,14(17). |
| MLA | Cai, Zhiyuan,et al."Seasonal piRNA Expression Profile Changes in the Testes of Plateau Zokor (Eospalax baileyi)".ANIMALS 14.17(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
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