Genetic Variations of MSTN and Callipyge in Tibetan Sheep: Implications for Early Growth Traits
文献类型：期刊论文
| 作者 | Zhao, Kai ; Li, Xue; Liu, Dehui; Wang, Lei; Pei, Quanbang; Han, Buying; Zhang, Zian; Tian, Dehong; Wang, Song; Zhao, Jincai
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| 刊名 | GENES
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| 出版日期 | 2024 |
| 卷号 | 15期号:7 |
| 英文摘要 | Tibetan sheep are integral to the ecosystems and livelihoods of the Tibetan Plateau; however, their breeding practices limit their production and growth. Candidate genes myostatin (MSTN)and Callipyge have been recognized as important for improving growth traits in livestock. This research examined the polymorphic loci of these genes in Tibetan sheep and their association with growth traits. The results indicated that SNP loci of MSTN could potentially be utilized as a molecular indicator for early growth traits in Tibetan sheep. Tibetan sheep are vital to the ecosystem and livelihood of the Tibetan Plateau; however, traditional breeding methods limit their production and growth. Modern molecular breeding techniques are required to improve these traits. This study identified a single nucleotide polymorphism (SNP) in myostatin (MSTN) and Callipyge in Tibetan sheep. The findings indicated notable associations between MSTN genotypes and growth traits including birth weight (BW), body length (BL), chest width (ChW), and chest circumference (ChC), as well as a particularly strong association with cannon circumference (CaC) at 2 months of age. Conversely, Callipyge polymorphisms did not have a significant impact on Tibetan sheep. Moreover, the analyses revealed a significant association between sex and BW or hip width (HW) at 2 months of age and ChW, ChC, and CaC at 4 months of age. Furthermore, the study's results suggested that the genotype of MSTN as a GA was associated with a notable sex effect on BW, while the genotype of Callipyge (CC) showed a significant impact of sex on CaC at 2 months of age. These results indicated that the SNP of MSTN could potentially serve as a molecular marker for early growth traits in Tibetan sheep. |
| 源URL | [http://210.75.249.4/handle/363003/62001]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Zhao, Kai,Li, Xue,Liu, Dehui,et al. Genetic Variations of MSTN and Callipyge in Tibetan Sheep: Implications for Early Growth Traits[J]. GENES,2024,15(7). |
| APA | Zhao, Kai.,Li, Xue.,Liu, Dehui.,Wang, Lei.,Pei, Quanbang.,...&Zhang, Fuqiang.(2024).Genetic Variations of MSTN and Callipyge in Tibetan Sheep: Implications for Early Growth Traits.GENES,15(7). |
| MLA | Zhao, Kai,et al."Genetic Variations of MSTN and Callipyge in Tibetan Sheep: Implications for Early Growth Traits".GENES 15.7(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
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