Optimized extraction, enrichment, identification and hypoglycemic effects of triterpenoid acids from Hippophae rhamnoides L pomace
文献类型：期刊论文
| 作者 | Tie, Fangfang; Dong, Qi; Zhu, Xiaohan; Ren, Lichengcheng; Liu, Zhenhua; Wang, Zhicheng; Wang, Honglun ; Hu, Na
|
| 刊名 | FOOD CHEMISTRY
 |
| 出版日期 | 2024 |
| 卷号 | 457 |
| 英文摘要 | The Hippophae rhamnoides L. pomace was generated in the production process for juice, wine of food industry. To expand the application of pomace, the extraction process optimization, enrichment and identification of triterpene acids were performed in this study. The extraction yield was 14.87% under optimal ultrasound -assisted extraction techniques performed via response surface methodology. The extract was subsequently purified to obtain the triterpenoid acid enrichment fraction (TPF) with the content of 75.23% +/- 1.45%. 13 triterpenoid acids were identified via UPLC-Triple-TOF MS/MS and further semi -quantified through comparison with triterpenoid acid standards. TPF exhibited a strong inhibitory effect on alpha-glucosidase with IC 50 value of 5.027 +/- 0.375 mu g/mL, as determined via enzyme inhibition experiment and molecular docking. Additionally, the TPF significantly reduced postprandial glucose levels, as revealed via carbohydrate tolerance tests, as well as ameliorate serum lipid profiles. Therefore, pomace may be a promising resource of functional food components with therapeutic and commercial values. |
| 源URL | [http://210.75.249.4/handle/363003/62010]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Tie, Fangfang,Dong, Qi,Zhu, Xiaohan,et al. Optimized extraction, enrichment, identification and hypoglycemic effects of triterpenoid acids from Hippophae rhamnoides L pomace[J]. FOOD CHEMISTRY,2024,457. |
| APA | Tie, Fangfang.,Dong, Qi.,Zhu, Xiaohan.,Ren, Lichengcheng.,Liu, Zhenhua.,...&Hu, Na.(2024).Optimized extraction, enrichment, identification and hypoglycemic effects of triterpenoid acids from Hippophae rhamnoides L pomace.FOOD CHEMISTRY,457. |
| MLA | Tie, Fangfang,et al."Optimized extraction, enrichment, identification and hypoglycemic effects of triterpenoid acids from Hippophae rhamnoides L pomace".FOOD CHEMISTRY 457(2024). |
入库方式： OAI收割
来源：西北高原生物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。