Characterization of alkaloids and phenolics in Nitraria roborowskii Kom. fruit by UHPLC-triple-TOF-MS/MS and its sucrase and maltase inhibitory effects
文献类型:期刊论文
作者 | Wu, Di; Jiang, Sirong; Wang, Gongyu; Wang, Luya; Wu, Li; Li, Jiaxin; Jia, Wenjiang; Liu, Liying; Xu, Jiyu; Zhang, Dejun |
刊名 | FOOD CHEMISTRY
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出版日期 | 2024 |
卷号 | 447 |
英文摘要 | Nitraria roborowskii Kom (NRK), with high economic and ecological value, is mainly distributed in the Qaidam Basin, China. However, research on its chemical components and bioactivities is still rare. In this study, its chemical constituents (52) including 10 beta-carboline alkaloids, nine cyclic peptides, three indole alkaloids, five pyrrole alkaloids, eight phenolic acids and 17 flavonoids were identified tentatively using UPLC-triple-TOF-MS/ MS. Notablely, one new beta-carboline alkaloid and five new cyclic peptides were confirmed using MS/MS fragmentation pathways. In addition, experiments in vitro indicated that NRK-C had strong maltase and sucrase inhibitory activities (IC50 of 0.202 and 0.103 mg/mL, respectively). Polysaccharide tolerance experiments confirmed NRK-C (400 mg/kg) was associated with decreased postprandial blood glucose (PBG) in diabetic mice. These results suggested that NRK fruit might be used as a functional ingredient in food products. |
源URL | [http://210.75.249.4/handle/363003/62072] ![]() |
专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
推荐引用方式 GB/T 7714 | Wu, Di,Jiang, Sirong,Wang, Gongyu,et al. Characterization of alkaloids and phenolics in Nitraria roborowskii Kom. fruit by UHPLC-triple-TOF-MS/MS and its sucrase and maltase inhibitory effects[J]. FOOD CHEMISTRY,2024,447. |
APA | Wu, Di.,Jiang, Sirong.,Wang, Gongyu.,Wang, Luya.,Wu, Li.,...&Yue, Huilan.(2024).Characterization of alkaloids and phenolics in Nitraria roborowskii Kom. fruit by UHPLC-triple-TOF-MS/MS and its sucrase and maltase inhibitory effects.FOOD CHEMISTRY,447. |
MLA | Wu, Di,et al."Characterization of alkaloids and phenolics in Nitraria roborowskii Kom. fruit by UHPLC-triple-TOF-MS/MS and its sucrase and maltase inhibitory effects".FOOD CHEMISTRY 447(2024). |
入库方式: OAI收割
来源:西北高原生物研究所
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