Pregnancy diagnosis and sex identification with urinary glycopatterns of two mammal species
文献类型：期刊论文
| 作者 | Yang, Jiayi; Jin, Shiyu; Zhang, Simeng; He, Shujun; Chen, Rui; Lei, Yinghu; Pan, Ruliang; Zhang, He; Wang, Zhongfu; Li, Zheng |
| 刊名 | ISCIENCE
 |
| 出版日期 | 2023 |
| 卷号 | 26期号:12 |
| 英文摘要 | Glycome in urine could be promising biomarkers for detecting pregnancy diagnosis and sex noninvasively for animals, especially for rare species. We explore the applicability of grouping golden snub-nosed monkeys by sex or diagnosing pregnancy based on their urinary glycopatterns, which are determined via lectin microarray combining mass spectrometry analysis. Sprague-Dawley rats are used to verify whether this approach and whether the glycomic biomarkers can be generalized to other mammalian species. The results show that, for both species, lectin microarray combining mass spectrometry can distinguish individuals' pregnancy status and sex; significant differences are found in the types, amounts, and terminal modification of glycans between pregnant and non-pregnant females and between females and males. This indicates the approach could be generalized to other mammalian species to group sex and detect pregnancy, yet the glycopatterns appear to be species-specific and markers developed from one species may not be directly applicable to another. |
| 源URL | [http://210.75.249.4/handle/363003/62145]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Yang, Jiayi,Jin, Shiyu,Zhang, Simeng,et al. Pregnancy diagnosis and sex identification with urinary glycopatterns of two mammal species[J]. ISCIENCE,2023,26(12). |
| APA | Yang, Jiayi.,Jin, Shiyu.,Zhang, Simeng.,He, Shujun.,Chen, Rui.,...&Guo, Songtao.(2023).Pregnancy diagnosis and sex identification with urinary glycopatterns of two mammal species.ISCIENCE,26(12). |
| MLA | Yang, Jiayi,et al."Pregnancy diagnosis and sex identification with urinary glycopatterns of two mammal species".ISCIENCE 26.12(2023). |
入库方式： OAI收割
来源：西北高原生物研究所
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