Nature-Derived Hollow Micron-Tubular Signal Tracers Conquering the Size Limitations for Multimodal Immunochromatographic Detection of Antibiotics
文献类型：期刊论文
| 作者 | Wang, Shaochi; Du, Ting; Liu, Sijie; Ma, Yiyue; Luo, Linpin; Zhu, Wenxin; Yang, Chengyuan; Sun, Jing; Zhang, Daohong; Wang, Jianlong |
| 刊名 | ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2023 |
| 卷号 | 95期号:46 |
| 英文摘要 | Developing signal tracers (STAs) with large size, multifunctionality, and high retention bioaffinity is believed to be a potential solution for achieving high-performance immunochromatographic assays (ICAs). However, the size limitations of STAs on strips are always a challenge because of the serious steric hindrance. Here, based on metal-quinone coordination and further metal etching, hollow micron-tubular STAs formed by natural alizarin and Fe3+ ions (named ALIFe) are produced to break through size limitations, provide more active sites, and achieve three-mode ICAs (ALIFe STAs-ICAs). Thanks to the special tubular morphology, ALIFe can successfully pass through the strip and provide an ideal signal intensity within 7 min at low mAb and probe dosages to achieve stable ICA analysis. Importantly, ALIFe shows excellent antibody enrichment and bioaffinity retention capability. With a proof-of-concept for streptomycin, the ALIFe STAs-ICAs showed the limit of detection (LOD) at 0.39 ng mL(-1) for colorimetric mode, 0.32 ng mL(-1) for catalytic mode, and 0.016 ng mL(-1) for photothermal mode with total recoveries ranging from 80.46 to 121.59% in mike and honey samples. We anticipate that our study will help expand the ideas for the design of high-performance STAs with large size and broaden the practical application of ICA. |
| 源URL | [http://210.75.249.4/handle/363003/62161]  |
| 专题 | 西北高原生物研究所_中国科学院西北高原生物研究所 |
| 推荐引用方式 GB/T 7714 | Wang, Shaochi,Du, Ting,Liu, Sijie,et al. Nature-Derived Hollow Micron-Tubular Signal Tracers Conquering the Size Limitations for Multimodal Immunochromatographic Detection of Antibiotics[J]. ANALYTICAL CHEMISTRY,2023,95(46). |
| APA | Wang, Shaochi.,Du, Ting.,Liu, Sijie.,Ma, Yiyue.,Luo, Linpin.,...&Wang, Jianlong.(2023).Nature-Derived Hollow Micron-Tubular Signal Tracers Conquering the Size Limitations for Multimodal Immunochromatographic Detection of Antibiotics.ANALYTICAL CHEMISTRY,95(46). |
| MLA | Wang, Shaochi,et al."Nature-Derived Hollow Micron-Tubular Signal Tracers Conquering the Size Limitations for Multimodal Immunochromatographic Detection of Antibiotics".ANALYTICAL CHEMISTRY 95.46(2023). |
入库方式： OAI收割
来源：西北高原生物研究所
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