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Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses

文献类型：期刊论文

作者Lv, Xiaojing1,2,3; Deng, Qinyou4; Chen, Lizhu4; Wang, Xin1; Han, Yijing5; Wu, Guiqing1; Liu, Yongliang1,2; Sun, Haiyue4; Li, Xuan4; He, Jinxia4
刊名AQUATIC TOXICOLOGY
出版日期2024-12-01
卷号277页码:14
关键词Haliotis discus hannai Ocean acidification Deltamethrin Integrated biomarker response
ISSN号0166-445X
DOI10.1016/j.aquatox.2024.107139
通讯作者Liu, Xiangquan(lxq6808@163.com) ; Yang, Dinglong(dlyang@yic.ac.cn)
英文摘要Ocean acidification (OA) and other environmental factors can collectively affect marine organisms. Deltamethrin (DM), a type II pyrethroid insecticide, has been widely detected in coastal and estuarine areas, while little attention has been given to the combined effects of DM and OA. In this study, Haliotis discus hannai was exposed to three pH levels (8.1, 7.7 and 7.4) and three DM nominal concentrations (0 mu g/L, 0.6 mu g/L and 6 mu g/L) for 14 and 28 days. The results indicated that experimental acidification and/or DM exposure led to impaired immune function and pathological damage. Additionally, acidified conditions and DM exposure induced oxidative stress, and gills are more sensitive than digestive glands. With increasing p CO 2 and DM nominal concentrations, superoxide dismutase (SOD) activity decreased, whereas catalase (CAT) and glutathione S-transferase (GST) activities increased in the gills. Moreover, the expression levels of Toll-like receptor (TLR) pathway-related genes were upregulated after exposure. Integrated biomarker response (IBR) analysis proved that acidified conditions and/or DM detrimentally affected the overall fitness of H. discus hannai, and co-exposure to experimental acidification and DM was the most stressful condition. This study emphasizes the necessity of incorporating OA in future pollutant environmental assessments to better elucidate the risks of environmental disturbance.
WOS关键词INTEGRATED BIOMARKER RESPONSE ; TOLL-LIKE RECEPTORS ; OXIDATIVE STRESS ; ANTIOXIDANT STATUS ; EASTERN OYSTERS ; MARINE BIVALVE ; FREE-RADICALS ; MECHANISMS ; MUSSEL ; CHALLENGE
WOS研究方向Marine & Freshwater Biology ; Toxicology
语种英语
WOS记录号WOS:001354791100001
资助机构National Science & Technology Fundamental Resources Investigation Program of China ; Strategic Priority Research Program of the Chinese Academy of Sciences ; National Natural Science Foundation of China ; Natural Science Foundation of Shandong Province ; Youth Innovation Promotion Association of CAS
源URL[http://ir.yic.ac.cn/handle/133337/37880]  
专题海岸带生物学与生物资源利用重点实验室
海岸带生物资源高效利用研究与发展中心
通讯作者Liu, Xiangquan; Yang, Dinglong
作者单位1.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res & Dev Ctr Efficient Utilizat Coastal Bioresour, Yantai 264003, Peoples R China
2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai 264003, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Shandong Marine Resource & Environm Res Inst, Yantai 264006, Shandong, Peoples R China
5.Ludong Univ, Sch Fisheries, Yantai 264025, Peoples R China
推荐引用方式
GB/T 7714		 Lv, Xiaojing,Deng, Qinyou,Chen, Lizhu,et al. Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses[J]. AQUATIC TOXICOLOGY,2024,277:14.
APA Lv, Xiaojing.,Deng, Qinyou.,Chen, Lizhu.,Wang, Xin.,Han, Yijing.,...&Zhao, Jianmin.(2024).Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses.AQUATIC TOXICOLOGY,277,14.
MLA Lv, Xiaojing,et al."Ocean acidification aggravates the toxicity of deltamethrin in Haliotis discus hannai: Insights from immune response, histopathology and physiological responses".AQUATIC TOXICOLOGY 277(2024):14.

入库方式： OAI收割

来源：烟台海岸带研究所

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