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A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder

文献类型：期刊论文

作者Li, Shuai-Biao9; Zhang, Jian-Biao8; Liu, Chao8; Wang, Ling-Ling5,6,7; Hu, Hui-Xin4,6,7; Chu, Min-Yi9; Wang, Yi6,7; Lv, Qin-Yu3,9; Lui, Simon S. Y.2; Yi, Zheng-Hui1,3,9
刊名EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
出版日期2024-11-02
页码12
关键词Negative symptoms Transdiagnostic Latent structure Major depressive disorder Bipolar disorder
ISSN号0940-1334
DOI10.1007/s00406-024-01934-5
通讯作者Yi, Zheng-Hui(yizhenghui1971@163.com) ; Chan, Raymond C. K.(rckchan@psych.ac.cn)
英文摘要Recent empirical findings suggest that negative symptoms are not limited to schizophrenia (SCZ) but also present in major depressive disorder (MDD) and bipolar disorder (BD) patients. Although SCZ patients generally showed a latent structure comprising the motivation and pleasure (MAP) and expression (EXP) factors, it remains unclear whether the same latent structure exists in MDD and BD patients. We administered the Clinical Assessment Interview for Negative Symptoms (CAINS) and the Brief Negative Symptom Scale (BNSS) to 179 MDD patients and 152 BD patients. Confirmatory Factor Analysis (CFA) was conducted to examine the one-factor model, the two-factor model of the MAP and the EXP domain, the five-factor model of anhedonia, avolition, asociality, alogia, and blunted affect, and the hierarchical model comprising the first-order five-factor, and the second-order two-factor (MAP and EXP factors). We further examined the correlations between demographics and the negative symptom dimensions found in the best factor model. The CFA showed that, when the CAINS and the BNSS were combined together, the two-factor model of MAP and EXP provided the best model fit than other competing models, in the MDD alone sample, BD alone sample, and the combined clinical sample. The two-factor model of the MAP and EXP appears to be a stable, transdiagnostic latent structure of negative symptoms across BD and MDD. Clarifying negative symptoms in MDD and BD can facilitate future research on the underlying neural mechanisms of the MAP and EXP dimensions.
收录类别SCI
WOS关键词CLINICAL-ASSESSMENT INTERVIEW ; OF-FIT INDEXES ; SCHIZOPHRENIA ; SCALE ; INDIVIDUALS ; DIMENSIONS ; VALIDITY ; APATHY
资助项目Jiangsu Provincial Key Research and Development Program
WOS研究方向Neurosciences & Neurology ; Psychiatry
语种英语
WOS记录号WOS:001346174300002
出版者SPRINGER HEIDELBERG
资助机构Jiangsu Provincial Key Research and Development Program
源URL[http://ir.psych.ac.cn/handle/311026/49255]  
专题心理研究所_中国科学院心理健康重点实验室
通讯作者Yi, Zheng-Hui; Chan, Raymond C. K.
作者单位1.Fudan Univ, Inst Mental Hlth, Shanghai, Peoples R China
2.Univ Hong Kong, Sch Clin Med, Dept Psychiat, Hong Kong, Peoples R China
3.Fudan Univ, Huashan Hosp, Sch Med, Dept Psychiat, Shanghai, Peoples R China
4.Beijing Forestry Univ, Sch Humanities & Social Sci, Dept Psychol, Beijing, Peoples R China
5.Shanghai Normal Univ, Sch Psychol, Shanghai, Peoples R China
6.Univ Chinese Acad Sci, Dept Psychol, Beijing, Peoples R China
7.Chinese Acad Sci, Inst Psychol, Neuropsychol & Appl Cognit Neurosci Lab, CAS Key Lab Mental Hlth, 16 Lincui Rd, Beijing, Peoples R China
8.Nantong Fourth Peoples Hosp, Nantong, Jiangsu, Peoples R China
9.Shanghai Jiao Tong Univ, Sch Med, Shanghai Mental Hlth Ctr, 600 South Wanping Rd, Shanghai, Peoples R China
推荐引用方式
GB/T 7714		 Li, Shuai-Biao,Zhang, Jian-Biao,Liu, Chao,et al. A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder[J]. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE,2024:12.
APA Li, Shuai-Biao.,Zhang, Jian-Biao.,Liu, Chao.,Wang, Ling-Ling.,Hu, Hui-Xin.,...&Chan, Raymond C. K..(2024).A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder.EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE,12.
MLA Li, Shuai-Biao,et al."A transdiagnostic approach of negative symptoms in psychiatric disorders: replication of a two-factor structure in major depressive disorder and bipolar disorder".EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2024):12.

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来源：心理研究所

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