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Fabrication of Raman reporter molecule-embedded magnetic SERS tag for ultrasensitive immunochromatographic monitoring of Cd ions and clenbuterol in complex samples

文献类型：期刊论文

作者Dong, Hao2,3,4; Bai, Wenlong3; Zheng, Shuai1,4; Wang, Qian4; Zhang, Long3,4; Hu, Qingyuan2,3; Liu, Yong3,4; Wang, Chongwen1; Wang, Shu4
刊名COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
出版日期2024-12-05
卷号702
关键词Magnetic SERS-ICA Raman reporter-embedded magnetic tag Clenbuterol Cd ion Simultaneous monitoring
ISSN号0927-7757
DOI10.1016/j.colsurfa.2024.135159
通讯作者Liu, Yong(liuyong1s@163.com) ; Wang, Chongwen(wangchongwen1987@126.com) ; Wang, Shu(wangshu@aiofm.ac.cn)
英文摘要A rapid, simple but sensitive analytical method for the simultaneous monitoring of heavy metal ions and illegal additives in complex samples remains lacking. We reported a difunctional capture-detection surface-enhanced Raman scattering (SERS) immunochromatographic assay (ICA) for the direct detection of the heavy metal residue Cd ion (Cd2+) and illegal additive clenbuterol (CLE) with high sensitivity and specificity herein. A novel magnetic SERS tag (Fe@RAu) with a Raman reporter molecule-embedded raspberry-like Au shell was fabricated via a one-step reduction reaction that not only simplified the fabrication of common magnetic SERS nanomaterials but also improved SERS activity to increase detection sensitivity. The difunctional SERS-ICA enabled the fast magnetic enrichment of the target small molecules in complex specimens and ultrasensitive and quantitative determination of CLE/Cd2+ on the two test lines of the ICA system. The limits of detection of the developed method for CLE and Cd2+ were as low as 0.48 and 1.88 pg/mL, respectively, and about 2000 and 500 times lower than those of conventional AuNP-based ICA strips. The excellent practicability of Fe@RAu-ICA for real food samples analysis was also demonstrated, revealing the potential of the proposed assay for rapid and onsite screening of small-molecule pollutants.
资助项目National Natural Science Founda-tion of China[82372348] ; National Natural Science Founda-tion of China[32200076] ; National Natural Science Founda-tion of China[82272423] ; Natural Science Foundation of Anhui Province[2208085MB29]
WOS研究方向Chemistry
语种英语
WOS记录号WOS:001301696200001
出版者ELSEVIER
资助机构National Natural Science Founda-tion of China ; Natural Science Foundation of Anhui Province
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/134920]  
专题中国科学院合肥物质科学研究院
通讯作者Liu, Yong; Wang, Chongwen; Wang, Shu
作者单位1.Southern Med Univ, Guangdong Prov Peoples Hosp, Guangdong Acad Med Sci, Dept Clin Lab Med, Guangzhou 510000, Peoples R China
2.China Natl Tobacco Qual Supervis & Test Ctr, Zhengzhou 450001, Peoples R China
3.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Hefei 230031, Peoples R China
4.Chinese Acad Sci, Hefei Inst Phys Sci, Hefei 230036, Peoples R China
推荐引用方式
GB/T 7714		 Dong, Hao,Bai, Wenlong,Zheng, Shuai,et al. Fabrication of Raman reporter molecule-embedded magnetic SERS tag for ultrasensitive immunochromatographic monitoring of Cd ions and clenbuterol in complex samples[J]. COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,2024,702.
APA Dong, Hao.,Bai, Wenlong.,Zheng, Shuai.,Wang, Qian.,Zhang, Long.,...&Wang, Shu.(2024).Fabrication of Raman reporter molecule-embedded magnetic SERS tag for ultrasensitive immunochromatographic monitoring of Cd ions and clenbuterol in complex samples.COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS,702.
MLA Dong, Hao,et al."Fabrication of Raman reporter molecule-embedded magnetic SERS tag for ultrasensitive immunochromatographic monitoring of Cd ions and clenbuterol in complex samples".COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 702(2024).

入库方式： OAI收割

来源：合肥物质科学研究院

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