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Multidisciplinary team quality improves the survival outcomes of locally

文献类型：期刊论文

作者Ma, Huiying2,3; Li, Haoyue2,3; Xu, Tongzhen2,3; Gao, Yuanhong4; Liu, Shixin5; Wang, Wenling6; Wei, Lichun7; Wang, Xishan8,9; Jiang, Liming8,10; Chi, Yihebali8,11
刊名RADIOTHERAPY AND ONCOLOGY
出版日期2024-11-01
卷号200
关键词Rectal cancer Multidisciplinary team quality Survival
ISSN号0167-8140
DOI10.1016/j.radonc.2024.110524
通讯作者Li, Yexiong(yexiong12@163.com) ; Zhou, Haitao(zhouhaitao01745@163.com) ; Tang, Yuan(tangyuan82@126.com) ; Jin, Jing(jinjing@csco.org.cn)
英文摘要Purpose: We sought to determine the association between multidisciplinary team (MDT) quality and survival of patients with locally advanced rectal cancer. Methods: In a post hoc analysis of the randomized phase III STELLAR trial, 464 patients with distal or middlethird, clinical tumor category cT3-4 and/or regional lymph node-positive rectal cancer who completed surgery were evaluated. Disease-free survival (DFS) and Overall survival (OS) were stratified by Multidisciplinary team (MDT) quality, which was also included in the univariable and multivariable analyses of DFS and OS. Results: According to the univariable analyses, a significantly worse DFS was associated with a fewer specialized medical disciplines participating in MDT (<5 vs > 5; P =0.049),a lower frequency of MDT meetings ( once a week; P =0.021) and a smaller MDT annual discussion volume of rectal cancer (<200 <200 vs > 200; P =0.039). In addition, a lower number of specialized medical disciplines participating in MDT (<5 vs > 5; P <0.001), a lower frequency of MDT meetings ( once a week; P <0.001) and a smaller MDT annual discussion volume of rectal cancer (<200 <200 vs > 200; P =0.001) were the variables associated with OS. These 3 factors were considered when assessing MDT quality, which was classified into 2 categories: high quality or general quality. Patients treated in hospitals with high MDT quality had longer 3-year OS (90.5 % vs 78.1 %; P =0.001) and similar 3-year DFS (70.3 % vs 61.3 %; P =0.109) compared to those treated in hospitals of the general MDT quality group. Furthermore, multivariable analyses e s revealed a significance for DFS (HR, 1.648; 95 % CI, 1.143-2.375; P =0.007) and OS (HR, 2.771; 95 % CI, 1.575-4.877; P <0.001) in MDT quality. Conclusions: The use of hospitals with optimized multidisciplinary infrastructure had a significant influence on survival of patients with locally advanced rectal cancer.
WOS关键词RECTAL-CANCER ; COLORECTAL-CANCER ; DECISION-MAKING ; PREOPERATIVE CHEMORADIOTHERAPY ; OPEN-LABEL ; CARE ; CHEMOTHERAPY ; MANAGEMENT ; CONFERENCES ; STATEMENT
WOS研究方向Oncology ; Radiology, Nuclear Medicine & Medical Imaging
语种英语
WOS记录号WOS:001317465900001
出版者ELSEVIER IRELAND LTD
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/135392]  
专题中国科学院合肥物质科学研究院
通讯作者Li, Yexiong; Zhou, Haitao; Tang, Yuan; Jin, Jing
作者单位1.Univ Sci & Technol China, USTC, Affiliated Hosp 1, Dept Radiat Oncol,Div Life Sci & Med, Hefei, Anhui, Peoples R China
2.Chinese Acad Med Sci CAMS & Peking Union Med Coll, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,State Key Lab Mol Oncol, Beijing, Peoples R China
3.Chinese Acad Med Sci CAMS & Peking Union Med Coll, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,Dept Radiat Oncol, Beijing, Peoples R China
4.Sun Yat Sen Univ, Collaborat Innovat Ctr Canc Med, Canc Ctr, Dept Radiat Oncol,State Key Lab Oncol South China, Guangzhou, Peoples R China
5.Jilin Prov Canc Hosp, Dept Radiat Oncol, Changchun, Peoples R China
6.Guizhou Med Univ, Affiliated Hosp, Dept Oncol, Guiyang, Peoples R China
7.Air Force Med Univ, Xijing Hosp, Dept Radiat Oncol, Xian, Peoples R China
8.CAMS & PUMC, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,State Key Lab Mol Oncol, Beijing, Peoples R China
9.CAMS & PUMC, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,Dept Colorectal Surg, Beijing, Peoples R China
10.CAMS & PUMC, Canc Hosp, Natl Canc Ctr, Natl Clin Res Ctr Canc,Dept Radiol, Beijing, Peoples R China
推荐引用方式
GB/T 7714		 Ma, Huiying,Li, Haoyue,Xu, Tongzhen,et al. Multidisciplinary team quality improves the survival outcomes of locally[J]. RADIOTHERAPY AND ONCOLOGY,2024,200.
APA Ma, Huiying.,Li, Haoyue.,Xu, Tongzhen.,Gao, Yuanhong.,Liu, Shixin.,...&Jin, Jing.(2024).Multidisciplinary team quality improves the survival outcomes of locally.RADIOTHERAPY AND ONCOLOGY,200.
MLA Ma, Huiying,et al."Multidisciplinary team quality improves the survival outcomes of locally".RADIOTHERAPY AND ONCOLOGY 200(2024).

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来源：合肥物质科学研究院

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