LTP-assisted fabrication of laccase-like Cu-MOF nanozyme-encoded array sensor for identification and intelligent sensing of bioactive components in food
文献类型：期刊论文
| 作者 | Liu, Chao1,2; Huang, Qing1,2
|
| 刊名 | BIOSENSORS & BIOELECTRONICS
 |
| 出版日期 | 2025 |
| 卷号 | 267 |
| 关键词 | Nanozyme Low-temperature plasma (LTP) Metal organic framework (MOF) Natural bioactive components Sensor array Intelligent sensing |
| ISSN号 | 0956-5663 |
| DOI | 10.1016/j.bios.2024.116784 |
| 通讯作者 | Huang, Qing(huangq@ipp.ac.cn) |
| 英文摘要 | Nanozymes are potential candidates for constructing sensors due to their adjustable activity, high stability, and high cost-effectiveness. However, due to the lack of reasonable means, designing and preparing efficient nanozymes remains challenging. Herein, inspired by the property of natural laccase, we applied the novel and facile low-temperature plasma (LTP) technology to fabricate a series of different base-ligand Cu metal organic framework (MOF) nanozymes (namely, A-Cu, G-Cu, C-Cu and T-Cu nanozymes) with laccase-like activity successfully. Owing to the different catalytic capacities of four types of base-Cu-MOF nanozymes in the response to five common effective bioactive substances, we constructed the nanozyme-encoded array sensor for the identification of different bioactive compounds. As a result, the four-channel colorimetric sensor array was constructed, in which four laccase-like nanozymes were utilized as the sensing units, achieving high-throughput, high-sensitivity and rapid detection/identification of five common bioactive compounds in the concentration range of 1.5-150 mu g mL(-1) through different color output patterns. It is worth noting that the as-prepared sensor array can successfully distinguish the natural bioactive compounds in a variety of real samples. Furthermore, with the assistance of smartphones, we also designed a portable smart sensing approach for detecting the bioactive compounds effectively in food. This study has therefore not only provided an effective way for preparation highly effectively nanozymes, but also established a new sensing platform for intelligent sensing of bioactive components in food. |
| 资助项目 | National Natural Science Foundation of China[11775272] ; National Natural Science Foundation of China[82260031] ; National Natural Science Foundation of China[T2250410383] |
| WOS研究方向 | Biophysics ; Biotechnology & Applied Microbiology ; Chemistry ; Electrochemistry ; Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001320476700001 |
| 出版者 | ELSEVIER ADVANCED TECHNOLOGY |
| 资助机构 | National Natural Science Foundation of China |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/135764]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Huang, Qing |
| 作者单位 | 1.Chinese Acad Sci, Inst Intelligent Machines, Hefei Inst Phys Sci, CAS Key Lab High Magnet Field & Iron Beam Phys Bio, Hefei 230031, Peoples R China 2.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Hefei 230026, Peoples R China |
| 推荐引用方式 GB/T 7714 | Liu, Chao,Huang, Qing. LTP-assisted fabrication of laccase-like Cu-MOF nanozyme-encoded array sensor for identification and intelligent sensing of bioactive components in food[J]. BIOSENSORS & BIOELECTRONICS,2025,267. |
| APA | Liu, Chao,&Huang, Qing.(2025).LTP-assisted fabrication of laccase-like Cu-MOF nanozyme-encoded array sensor for identification and intelligent sensing of bioactive components in food.BIOSENSORS & BIOELECTRONICS,267. |
| MLA | Liu, Chao,et al."LTP-assisted fabrication of laccase-like Cu-MOF nanozyme-encoded array sensor for identification and intelligent sensing of bioactive components in food".BIOSENSORS & BIOELECTRONICS 267(2025). |
入库方式： OAI收割
来源：合肥物质科学研究院
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