Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails
文献类型：期刊论文
| 作者 | Zhang, Ying1,2; Chen, Zhaoquan3; Shao, Changsheng2,3; Huang, Qing1,2
|
| 刊名 | APPLIED PHYSICS LETTERS
 |
| 出版日期 | 2024-06-10 |
| 卷号 | 124 |
| ISSN号 | 0003-6951 |
| DOI | 10.1063/5.0206605 |
| 通讯作者 | Huang, Qing(huangq@ipp.ac.cn) |
| 英文摘要 | This study aimed to apply a portable pulsed cold air plasma jet (PP-CAPJ) device in onychomycosis treatment and investigate its effect and mechanism of action. Based on the characteristics of onychomycosis, we selected Trichophyton rubrum (T. rubrum) for our experiments and explored the inactivation ability of the PP-CAPJ on T. rubrum that grew in nails. We found that the PP-CAPJ could effectively kill T. rubrum in the nails, and for T. rubrum in 1.5 mm thick nails, 300 spark discharges could kill almost all the fungi. The fungicidal mechanism is mainly due to the ability of shock waves from the PP-CAPJ to impose pressure on the nail and destroy the cell membrane of T. rubrum. This work has therefore demonstrated the use of an effective and noninvasive approach for the treatment of onychomycosis. |
| WOS关键词 | GENETIC-TRANSFORMATION ; ATMOSPHERIC PLASMA ; ONYCHOMYCOSIS ; MECHANISMS |
| 资助项目 | National Natural Science Foundation of China10.13039/501100001809[11635013] ; National Natural Science Foundation of China |
| WOS研究方向 | Physics |
| 语种 | 英语 |
| WOS记录号 | WOS:001248285000006 |
| 出版者 | AIP Publishing |
| 资助机构 | National Natural Science Foundation of China10.13039/501100001809 ; National Natural Science Foundation of China |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/136239]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Huang, Qing |
| 作者单位 | 1.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Hefei 230026, Peoples R China 2.Chinese Acad Sci, Hefei Inst Phys Sci, CAS Key Lab High Magnet Field & Iron Beam Phys Bio, Hefei 230031, Peoples R China 3.Anhui Univ Technol, Anhui Key Lab Elect Drive & Power Elect, Maanshan 243032, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Ying,Chen, Zhaoquan,Shao, Changsheng,et al. Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails[J]. APPLIED PHYSICS LETTERS,2024,124. |
| APA | Zhang, Ying,Chen, Zhaoquan,Shao, Changsheng,&Huang, Qing.(2024).Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails.APPLIED PHYSICS LETTERS,124. |
| MLA | Zhang, Ying,et al."Study of the effect of shock wave from a portable pulsed cold air plasma jet device on inactivation of Trichophyton rubrum in nails".APPLIED PHYSICS LETTERS 124(2024). |
入库方式： OAI收割
来源：合肥物质科学研究院
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