Design of microfluidic fluorescent sensor arrays for real-time and synchronously visualized detection of multi-component heavy metal ions
文献类型：期刊论文
| 作者 | Li, Lingfei3; Xu, Shihao3; Li, Xingzhen1,3; Gao, Hongcheng3; Yang, Liang2,3; Jiang, Changlong2,3
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| 刊名 | CHEMICAL ENGINEERING JOURNAL
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| 出版日期 | 2024-08-01 |
| 卷号 | 493 |
| 关键词 | Ultra -sensitive Microfluidic Fluorescent Sensor arrays Simultaneous detection |
| ISSN号 | 1385-8947 |
| DOI | 10.1016/j.cej.2024.152636 |
| 通讯作者 | Xu, Shihao(xush@mail.ustc.edu.cn) ; Yang, Liang(yangliang@iim.ac.cn) ; Jiang, Changlong(cljiang@iim.ac.cn) |
| 英文摘要 | The majority of the environmental heavy metal ions exist in the form of multi -components, and the current single -to -single rapid detection methods are unable to meet the needs of simultaneous multi -component detection. Here, we have designed a microfluidic fluorescence sensor array by combining microfluidic sensing and organic fluorescent switches for the real-time and simultaneous visual detection of multi -component heavy metal ions. A series of "light -up " organic molecular probes was designed and synthesized, exhibiting a strong ability to bind heavy metal ions and resulting in the opening of probe fluorescence. Meanwhile, we design microfluidic sensor plate, the patterned path of the microfluidic plate has drainage channel wall and 2.70 degrees downward slope, which can enable the samples to quickly reach the detection area. By loading organic molecular probes into the detection area, the microfluidic sensor array achieves simultaneous detection of four heavy metal ions. Combined with intelligent terminal, read and analyze the RGB color mode (RGB) results of detection, obtain quantitative information. The microfluidic fluorescence sensor array developed here can meet the requirements for in situ and semi -quantitative detection of a range of heavy metal ions with a low detection limit, fast reaction speed, and without the need for pretreatment. It represents a novel engineering technology approach for real-time detection of multi -components in the environment. |
| WOS关键词 | ANALYTICAL DEVICE ; PROBE |
| 资助项目 | National Natural Science Foundation of China[22274158] ; National Natural Science Foundation of China[U23A20265] ; National Key Research and Development Program of China[2021YFD2000202] ; Natural Science Foundation of Anhui Provincial[2208085 MB30] ; Anhui Provincial Key Research and Development Program[2022 k07020010] |
| WOS研究方向 | Engineering |
| 语种 | 英语 |
| WOS记录号 | WOS:001250399300001 |
| 出版者 | ELSEVIER SCIENCE SA |
| 资助机构 | National Natural Science Foundation of China ; National Key Research and Development Program of China ; Natural Science Foundation of Anhui Provincial ; Anhui Provincial Key Research and Development Program |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/136388]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Xu, Shihao; Yang, Liang; Jiang, Changlong |
| 作者单位 | 1.Chinese Acad Sci, Hefei Inst Phys Sci, Key Lab Photovolta & Energy Conservat Mat, Hefei 230031, Peoples R China 2.Univ Sci & Technol China, Dept Chem, Hefei 230026, Peoples R China 3.Chinese Acad Sci, Hefei Inst Phys Sci, Inst Solid State Phys, Hefei 230031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Li, Lingfei,Xu, Shihao,Li, Xingzhen,et al. Design of microfluidic fluorescent sensor arrays for real-time and synchronously visualized detection of multi-component heavy metal ions[J]. CHEMICAL ENGINEERING JOURNAL,2024,493. |
| APA | Li, Lingfei,Xu, Shihao,Li, Xingzhen,Gao, Hongcheng,Yang, Liang,&Jiang, Changlong.(2024).Design of microfluidic fluorescent sensor arrays for real-time and synchronously visualized detection of multi-component heavy metal ions.CHEMICAL ENGINEERING JOURNAL,493. |
| MLA | Li, Lingfei,et al."Design of microfluidic fluorescent sensor arrays for real-time and synchronously visualized detection of multi-component heavy metal ions".CHEMICAL ENGINEERING JOURNAL 493(2024). |
入库方式： OAI收割
来源：合肥物质科学研究院
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