Application of magnetotactic bacteria as engineering microrobots: Higher delivery efficiency of antitumor medicine
文献类型：期刊论文
| 作者 | Zhang, Jing2,3; Wang, Charles1; Zhang, Yaoyao2,3; Xia, Haining2,3; Wang, Yujuan2,4 ; Ma, Kun2,4; Wang, Junfeng2,3,4
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| 刊名 | CHINESE CHEMICAL LETTERS
 |
| 出版日期 | 2024-10-01 |
| 卷号 | 35 |
| 关键词 | Magnetotactic bacteria Engineering microrobot Tumor treatment Drug delivery Bioconjugation |
| ISSN号 | 1001-8417 |
| DOI | 10.1016/j.cclet.2023.109420 |
| 通讯作者 | Ma, Kun(makun@hmfl.ac.cn) |
| 英文摘要 | For a significant duration, enhancing the efficacy of cancer therapy has remained a critical concern. Magnetotactic bacteria (MTB), often likened to micro-robots, hold substantial promise as a drug delivery system. MTB, classified as anaerobic, aquatic, and gram-negative microorganisms, exhibit remarkable motility and precise control over their internal biomineralization processes. This unique ability results in the formation of magnetic nanoparticles arranged along filamentous structures in a catenary fashion, enclosed within a membrane. These bacteria possess distinctive biochemical properties that facilitate their precise positioning within complex environments. By harnessing these biochemical attributes, MTB could potentially offer substantial advantages in the realm of cancer therapy. This article reviews the drug delivery capabilities of MTB in tumor treatment and explores various applications based on their inherent properties. The objective is to provide a comprehensive understanding of MTB-driven drug delivery and stimulate innovative insights in this field. (c) 2024 Published by Elsevier B.V. on behalf of Chinese Chemical Society and Institute of Materia Medica, Chinese Academy of Medical Sciences. |
| WOS关键词 | MAGNETOSOME FORMATION ; TARGETED DELIVERY ; CANCER-CELLS ; DRUG ; NANOPARTICLES ; THERAPY ; HYPOXIA ; GROWTH ; NANOLIPOSOMES ; INHIBITION |
| 资助项目 | National Natural Science Foundation of China[3190110313] ; Special Foundation of President of the Chinese Academy of Sciences[YZJJ2022QN44] ; HFIPS Director's Fund[YZJJQY202201] ; HFIPS Director's Fund[E16CWK123X1] ; Heye Health Technology Chong Ming Project[HYCMP-2022012] |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001271993300001 |
| 出版者 | ELSEVIER SCIENCE INC |
| 资助机构 | National Natural Science Foundation of China ; Special Foundation of President of the Chinese Academy of Sciences ; HFIPS Director's Fund ; Heye Health Technology Chong Ming Project |
| 源URL | [http://ir.hfcas.ac.cn:8080/handle/334002/137137]  |
| 专题 | 中国科学院合肥物质科学研究院 |
| 通讯作者 | Ma, Kun |
| 作者单位 | 1.Univ Calif San Diego, La Jolla, CA 92093 USA 2.Chinese Acad Sci, Hefei Inst Phys Sci, High Magnet Field Lab, CAS Key Lab High Magnet Field & Ion Beam Phys Biol, Hefei 230031, Peoples R China 3.Univ Sci & Technol China, Hefei 230026, Peoples R China 4.Int Magnetobiol Frontier Res Ctr, Hefei 230031, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Jing,Wang, Charles,Zhang, Yaoyao,et al. Application of magnetotactic bacteria as engineering microrobots: Higher delivery efficiency of antitumor medicine[J]. CHINESE CHEMICAL LETTERS,2024,35. |
| APA | Zhang, Jing.,Wang, Charles.,Zhang, Yaoyao.,Xia, Haining.,Wang, Yujuan.,...&Wang, Junfeng.(2024).Application of magnetotactic bacteria as engineering microrobots: Higher delivery efficiency of antitumor medicine.CHINESE CHEMICAL LETTERS,35. |
| MLA | Zhang, Jing,et al."Application of magnetotactic bacteria as engineering microrobots: Higher delivery efficiency of antitumor medicine".CHINESE CHEMICAL LETTERS 35(2024). |
入库方式： OAI收割
来源：合肥物质科学研究院
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