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On the evolutionary trail of MagRs

文献类型：期刊论文

作者Zhang, Jing1,3; Chang, Yafei1,3; Zhang, Peng1,3; Zhang, Yanqi1,3; Wei, Mengke5; Han, Chenyang5; Wang, Shun5; Lu, Hui-Meng4; Cai, Tiantian1,2,3; Xie, Can1,2
刊名ZOOLOGICAL RESEARCH
出版日期2024-07-18
卷号45
关键词Magnetoreception Magnetoreceptor (MagR) Iron-sulfur cluster Stability Evolutionary biochemistry
ISSN号2095-8137
DOI10.24272/j.issn.2095-8137.2024.074
通讯作者Cai, Tiantian(tiantiancai@zju.edu.cn) ; Xie, Can(canxie@zju.edu.cn)
英文摘要Magnetic sense, or termed magnetoreception, has evolved in a broad range of taxa within the animal kingdom to facilitate orientation and navigation. MagRs, highly conserved A-type iron-sulfur proteins, are widely distributed across all phyla and play essential roles in both magnetoreception and iron-sulfur cluster biogenesis. However, the evolutionary origins and functional diversification of MagRs from their prokaryotic ancestor remain unclear. In this study, MagR sequences from 131 species, ranging from bacteria to humans, were selected for analysis, with 23 representative sequences covering species from prokaryotes to Mollusca, Arthropoda, Osteichthyes, Reptilia, Aves, and mammals chosen for protein expression and purification. Biochemical studies revealed a gradual increase in total iron content in MagRs during evolution. Three types of MagRs were identified, each with distinct iron and/or iron-sulfur cluster binding capacity and protein stability, indicating continuous expansion of the functional roles of MagRs during speciation and evolution. This evolutionary biochemical study provides valuable insights into how evolution shapes the physical and chemical properties of biological molecules such as MagRs and how these properties influence the evolutionary trajectories of MagRs.
WOS关键词IRON-SULFUR CLUSTER ; ELECTRON-TRANSFER ; ASSEMBLY PROTEIN ; MAGNETORECEPTOR MAGR ; MAGNETIC COMPASS ; BINDING ACTIVITY ; ISCA ; ORIENTATION ; NAVIGATION ; SEQUENCE
资助项目National Natural Science Foundation of China[31640001] ; National Natural Science Foundation of China[T2350005] ; Ministry of Science and Technology of China[2021ZD0140300] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[Y96XC11131] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[E26CCG27] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[E26CCD15] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[E36CWGBR24B] ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences[E36CZG14132]
WOS研究方向Zoology
语种英语
WOS记录号WOS:001272410200008
出版者SCIENCE PRESS
资助机构National Natural Science Foundation of China ; Ministry of Science and Technology of China ; Presidential Foundation of Hefei Institutes of Physical Science, Chinese Academy of Sciences
源URL[http://ir.hfcas.ac.cn:8080/handle/334002/137237]  
专题中国科学院合肥物质科学研究院
通讯作者Cai, Tiantian; Xie, Can
作者单位1.Univ Sci & Technol China, Sci Isl Branch, Grad Sch, Hefei 230036, Anhui, Peoples R China
2.Zhejiang Univ, Inst Quantum Sensing, Hangzhou 310027, Zhejiang, Peoples R China
3.Chinese Acad Sci, High Magnet Field Lab, Hefei Inst Phys Sci, Hefei 230031, Anhui, Peoples R China
4.Northwestern Polytech Univ, Sch Life Sci, Key Lab Space Biosci & Biotechnol, Xian 710072, Shaanxi, Peoples R China
5.Anhui Univ, Inst Phys Sci & Informat Technol, Hefei 230039, Anhui, Peoples R China
推荐引用方式
GB/T 7714		 Zhang, Jing,Chang, Yafei,Zhang, Peng,et al. On the evolutionary trail of MagRs[J]. ZOOLOGICAL RESEARCH,2024,45.
APA Zhang, Jing.,Chang, Yafei.,Zhang, Peng.,Zhang, Yanqi.,Wei, Mengke.,...&Xie, Can.(2024).On the evolutionary trail of MagRs.ZOOLOGICAL RESEARCH,45.
MLA Zhang, Jing,et al."On the evolutionary trail of MagRs".ZOOLOGICAL RESEARCH 45(2024).

入库方式： OAI收割

来源：合肥物质科学研究院

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