Isolation and identification of antimicrobial metabolites from sea anemone-derived fungus Emericella sp. SMA01
文献类型：CNKI期刊论文
| 作者 | Yang YUE ; Huahua YU; Rongfeng LI; Linfeng HU; Song LIU; Rong'e XING; Pengcheng LI
|
| 发表日期 | 2021-05-15 |
| 出处 | Journal of Oceanology and Limnology
 |
| 关键词 | sea anemone symbiotic fungi phenazine-1-carboxylic acid antimicrobial activity |
| 英文摘要 | Marine symbiotic fungi represent an intriguing source of discovery of novel secondary metabolites with various biological activities. Sea anemones are benthic marine invertebrates, however, the cultivable symbiotic fungi residing in the sea anemones are paid few attentions compared to those derived from their cnidarian counterparts. Here we show the identification of antimicrobial secondary metabolites from the sea anemone-derived symbiotic fungi. Out offive isolated fungal strains, only the strain SMA01 showed strong antimicrobial activities, which was assigned into the genus Emericella based on the morphological characteristics and the ITS sequencing. Media swift from liquid fermentation to solid rice medium presented little influence on its antibacterial activity. A chemical investigation of the ethyl acetate extract of the Emericella sp. SMA01 led to discovery of the primary antibiotic metabolite phenazine-1-carboxylic acid. The IC_(50) values of the phenazine-1-carboxylic acid against Phytophthora capsici, Gibberella zeae, and Verticillium dahliae were determined to be 23.26–53.89 μg/mL. To the best of our knowledge, this was the first report of Emericella sp. in sea anemones. The current study may benefit understanding of the defensive chemical interactions between the symbiotic fungi and their host sea anemones. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the National Natural Science Foundation of China (Nos. 41376004, 41406152) ; the Key Research and Development Project of Shandong Province (No. 2018GHY115008) ; the Youth Innovation Promotion Association of CAS ; the Scientific and Technological Innovation Project (No. 2015ASKJ02) |
| 卷 | v.39期:03页:227-236 |
| 语种 | 英文; |
| 分类号 | Q936 |
| ISSN号 | 2096-5508 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/187770]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.KeyLaboratoryofExperimentalMarineBiology,CenterforOceanMega-Science,InstituteofOceanology,ChineseAcademyofSciences 2.LaboratoryforMarineDrugsandBioproducts,PilotQingdaoNationalLaboratoryforMarineScienceandTechnology 3.SchoolofChemistryandChemicalEngineering,HenanInstituteofScienceandTechnology |
| 推荐引用方式 GB/T 7714 | Yang YUE,Huahua YU,Rongfeng LI,et al. Isolation and identification of antimicrobial metabolites from sea anemone-derived fungus Emericella sp. SMA01. 2021. |
入库方式： OAI收割
来源：海洋研究所
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