bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas
文献类型:CNKI期刊论文
作者 | CHEN Na; LI Li; LI Chenghua; LIN Zhihua; MENG Jie![]() |
发表日期 | 2020-05-15 |
出处 | Journal of Oceanology and Limnology
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关键词 | Crassostrea gigas basic helix-loop-helix (b HLH) re-sequencing single nucleotide polymorphism(SNP) shot growth traits |
英文摘要 | The basic helix-loop-helix(b HLH) genes encode a large superfamily of transcription factors in the Pacific oyster( Crassostrea gigas), and play a very important role in regulation of growth and development. To investigate the oyster growth traits and the associations with b HLH genes variations, we analyzed the gene polymorphisms-traits association in a wild population, and confirmed the results in another independent wild population by targeted gene re-sequencing and SNPshot analysis. After screening the single nucleotide polymorphisms(SNPs) in three candidate genes of the b HLH family(88 b HLH genes in two wild oyster populations in total), we identified the allele Cg Lobl HLH4-T/G located in the exon of the Cg Lobl HLH4 gene. This allele is a non-synonymous mutation(Phe/Leu) with an extremely significant association with shell width( P <0.01) and allele G is beneficial to shell width. This SNP on the Cg Lobl HLH4 gene might have a potential value as a genetic marker of growth traits that could be used in breeding in C. gigas in the future. |
文献子类 | CNKI期刊论文 |
资助机构 | Supported by the National Key R&D Program of China (No. 2018YFD0901400) ; the National Natural Science Foundation of China (No. 31672678) ; the Ningbo Municipal Science and Technology International Cooperation Research Projects (No. 2016D10017) ; the Zhejiang Provincial Major Program of Science and Technology (No. 2016C02055-9) |
卷 | v.38期:03页:273-279 |
语种 | 英文; |
分类号 | Q953 |
ISSN号 | 2096-5508 |
源URL | [http://ir.qdio.ac.cn/handle/337002/188228] ![]() |
专题 | 中国科学院海洋研究所 |
作者单位 | 1.SchoolofMarineSciences,NingboUniversity 2.ZhejiangKeyLaboratoryofAquaticGermplasmResources,CollegeofBiological&EnvironmentalSciences,ZhejiangWanliUniversity 3.KeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences |
推荐引用方式 GB/T 7714 | CHEN Na,LI Li,LI Chenghua,et al. bHLH genes polymorphisms and their association with growth traits in the Pacific oyster Crassostrea gigas. 2020. |
入库方式: OAI收割
来源:海洋研究所
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