Chemical constituents of marine mangrove-derived endophytic fungus Alternaria tenuissima EN-192
文献类型：CNKI期刊论文
| 作者 | Sun H(孙红); Gao SS(高书山); Li XM(李晓明); Li CS(李春顺); Wang BG(王斌贵)
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| 发表日期 | 2013-03-15 |
| 出处 | Chinese Journal of Oceanology and Limnology
 |
| 关键词 | endophytic fungus Alternaria tenuissima Rhizophora stylosa indole-diterpene |
| 英文摘要 | A chemical investigation of the ethyl acetate extract of the fermentation broth of Alternaria tenuissima EN-192,an endophytic fungus obtained from the stems of the marine mangrove plant Rhizophora stylosa,resulted in the isolation of nine known secondary metabolites,including four indole-diterpenoids:penijanthine A(1),paspaline(2),paspalinine(3),and penitrem A(4);three tricycloalternarene derivatives:tricycloalternarene 3a(5),tricycloalternarene 1b(6),and tricycloalternarene 2b(7);and two alternariol congeners:djalonensone(8) and alternariol(9).The chemical structures of these metabolites were characterized through a combination of detailed spectroscopic analyses and their comparison with reports from the literature.The inhibitory activities of each isolated compound against four bacteria were evaluated and compounds 5 and 8 displayed moderate activity against the aquaculture pathogenic bacterium Vibrio anguillarum,with inhibition zone diameters of 8 and 9 mm,respectively,at 100 μg/disk.To the best of our knowledge,this is the first report on the secondary metabolites of mangrove-derived Alternaria tenuissima and also the first report of the isolation of indole-diterpenoids from fungal genus Alternaria. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the National Natural Science Foundation of China(Nos.30910103914,31270403) ; the Ministry of Science and Technology(No.2010CB833802) |
| 卷 | v.31期:02页:220-226 |
| 语种 | 英文; |
| 分类号 | S435.72 |
| ISSN号 | 0254-4059 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/190934]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.GraduateUniversityofChineseAcademyofSciences 2.KeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences |
| 推荐引用方式 GB/T 7714 | Sun H,Gao SS,Li XM,et al. Chemical constituents of marine mangrove-derived endophytic fungus Alternaria tenuissima EN-192. 2013. |
入库方式： OAI收割
来源：海洋研究所
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