Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor
文献类型：CNKI期刊论文
| 作者 | Tan XG(谭训刚) ; Zhang YQ(张玉青); Sun W(孙威); Zhang PJ(张培军); Xu YL(徐永立)
|
| 发表日期 | 2012-03-15 |
| 出处 | Chinese Journal of Oceanology and Limnology
 |
| 关键词 | flounder FoxD5 muscle over-expression in situ hybridization myogenic regulatory factor |
| 英文摘要 | As one member of winged helix domain transcription factors, FoxD5 was reported to be a trunk organizer. Recent study showed that zebrafish foxd5 is expressed in the somites. To further understand the function of FoxD5 in fish muscle development, the FoxD5 gene was isolated from flounder. Its expression pattern was analyzed by in situ hybridization, while its function in regulating myogenic regulatory factor, MyoD, was analyzed by ectopic expression. It showed that flounder FoxD5 was firstly expressed in the tailbud, adaxial cells, and neural plate of the head. In flounder embryo, FoxD5 is expressed not only in forebrain but also in somite cells that will form muscle in the future. When flounder FoxD5 was over-expressed in zebrafish by microinjection, the expression of zebrafish MyoD in the somites was reduced, suggesting that FoxD5 is involved in myogenesis by regulating the expression of MyoD. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the Natural Science Foundation of Shandong Province,China(No.Y2008E12) ; the National Basic Research Program of China(973Program)(No.2010CB126304) |
| 卷 | v.30期:02页:96-104 |
| 语种 | 英文; |
| 分类号 | S917.4 |
| ISSN号 | 0254-4059 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/191333]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.EMBLC,InstituteofOceanology,ChineseAcademyofSciences 2.GraduateUniversityofChineseAcademyofSciences |
| 推荐引用方式 GB/T 7714 | Tan XG,Zhang YQ,Sun W,et al. Characterization of flounder (Paralichthys olivaceus) FoxD5 and its function in regulating myogenic regulatory factor. 2012. |
入库方式： OAI收割
来源：海洋研究所
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