Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure
文献类型：CNKI期刊论文
| 作者 | Wang XY(王晓宇); Yang HS(杨红生) ; Liu GB(刘广斌); Wang Q(王清)
|
| 发表日期 | 2011-09-15 |
| 出处 | Chinese Journal of Oceanology and Limnology
 |
| 关键词 | ACP ALP antioxidant enzymes cadmium Mactra vereformis MDA |
| 英文摘要 | To assess the toxicity of heavy metal pollution to marine intertidal shellfish, enzymatic responses and lipid peroxidation were investigated in the clam Mactra vereformis exposed to cadmium under laboratory conditions. Three antioxidant enzymes (superoxide dismutase, SOD; catalase, CAT; glutathione peroxidase, GPx), two immune defense enzymes (acid phosphatase, ACP; alkaline phosphatase, ALP), and one lipid peroxidation product (malondialdehyde, MDA) were measured in the gills and the hepatopancreas of the clam exposed to 0, 25, 75, and 125 μg/L cadmium for 0, 1, 3, 5, and 7 d. The results show that the concentrations of antioxidant enzymes in the organs soared to a peak value on the first day and then decreased afterwards in most cases. CAT and GPx activities in the hepatopancreas were higher than in the gills, but the SOD activity was lower in the hepatopancreas. ACP activity was unchanged until Day 3 in the hepatopancreas and until Day 5 in gills, when it began to increase. ALP activity showed no significant relationship with Cd treatment. MDA concentrations increased in the two tissues after Cd exposure, peaked on Day 3 in gills, and on Day 5 in hepatopancreas. These observations show that changes in the activities of antioxidant enzymes and ACP reflect the time course of oxidative stress in the clam caused by Cd, and could be used as potential biomarkers for ecotoxicological bioassays of heavy metals. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the National Basic Research Program of China (973 Program) (No. 2007CB407305) ; the Tianjin Program for Marine Development by Reliance on Science and Technology (No. kx2010-4) ; the National Marine Public Welfare Research Project of China (No. 200805069) ; the Natural Science Fundation for Creative Research Groups (No. 40821004) ; the Knowledge Innovation Key Projects of Chinese Academy of Sciences (No. KZCX2-YW-Q07-03) |
| 卷 | v.29期:05页:67-75 |
| 语种 | 英文; |
| 分类号 | S917.4 |
| ISSN号 | 0254-4059 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/191563]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.KeyLaboratoryofMarineEcologyandEnvironmentalSciences,InstituteofOceanology,ChineseAcademyofSciences 2.TianjinFisheriesResearchInstitute 3.MaricultureInstituteofShandongProvince |
| 推荐引用方式 GB/T 7714 | Wang XY,Yang HS,Liu GB,et al. Enzyme responses and lipid peroxidation in gills and hepatopancreas of clam Mactra vereformis, following cadmium exposure. 2011. |
入库方式： OAI收割
来源：海洋研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。