Characterization of DYRK2(dual-specificity tyrosine-phosphorylation-regulated kinase 2) from Zebrafish(Dario rerio)
文献类型：CNKI期刊论文
| 作者 | Sun W(孙威); Tan XG(谭训刚) ; Zhang PJ(张培军); Zhang YQ(张玉青); Xu YL(徐永立)
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| 发表日期 | 2010-08-15 |
| 出处 | Chinese Journal of Oceanology and Limnology
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| 关键词 | zebrafish DYRK2 in-situ hybridization muscle development |
| 英文摘要 | Proteins of the DYRK(dual-specificity tyrosine-phosphorylation-regulated kinase) family are characterized by the presence of a conserved kinase domain and N-terminal DH box.DYRK2 is involved in regulating key developmental and cellular processes,such as neurogenesis,cell proliferation,cytokinesis,and cellular differentiation.Herein,we report that the ortholog of DYRK2 found in zebrafish shares about 70% identity with that of human,mouse,and chick.RT-PCR showed that DYRK2 is expressed maternally and zygotically.In-situ hybridization results show that DYRK2 is expressed in somite cells that will develop into muscles.Our results provide preliminary evidence for investigating the in-vivo function of DYRK2 in zebrafish muscle development. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the Open Research Fund Program of Key Laboratory of Marine Drugs(Ocean University of China),Grant of Ministry of Education to X.TAN,KLMD(OUC)200609 ; the National Natural Science Foundation of China(No.30970423) |
| 卷 | v.28期:04页:10-14 |
| 语种 | 英文; |
| 分类号 | S917.4 |
| ISSN号 | 0254-4059 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/192011]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.InstituteofOceanology,ChineseAcademyofSciences 2.GraduateSchool,ChineseAcademyofSciences |
| 推荐引用方式 GB/T 7714 | Sun W,Tan XG,Zhang PJ,et al. Characterization of DYRK2(dual-specificity tyrosine-phosphorylation-regulated kinase 2) from Zebrafish(Dario rerio). 2010. |
入库方式： OAI收割
来源：海洋研究所
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