Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
文献类型：CNKI期刊论文
| 作者 | Tian MQ(田敏卿); Dai HF(戴好富); Li XM(李晓明); Wang BG(王斌贵)
|
| 发表日期 | 2009-05-15 |
| 出处 | Chinese Journal of Oceanology and Limnology
 |
| 关键词 | mangrove Sonneratia caseolaris chemical constituents cytotoxic assay |
| 英文摘要 | Twenty-four compounds including eight steroids (1–8), nine triterpenoids (9–16, 24), three flavonoids (20–22), and four benzenecarboxylic derivatives (17–19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4–20 and 22–24 were isolated and identified for the first time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3′,4′,5,7-tetrahydroxyflavone) exhibited significant activity with IC50 2.8 μg/mL, while oleanolic acid (14), 3,3′-di-O-methyl ether ellagic acid (18), and 3,3′,4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites. |
| 文献子类 | CNKI期刊论文 |
| 资助机构 | Supported by the National Natural Science Foundation of China (No. 30770234) ; Knowledge Innovation Program of Chinese Academy of Sciences (KZCX2-YW-211-04) ; Department of Science and Technology of Shandong Province (No.2006GG2205023) |
| 卷 | v.27期:02页:106-114 |
| 语种 | 英文; |
| 分类号 | Q946 |
| ISSN号 | 0254-4059 |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/192582]  |
| 专题 | 中国科学院海洋研究所 |
| 作者单位 | 1.KeyLaboratoryofExperimentalMarineBiology,InstituteofOceanology,ChineseAcademyofSciences 2.GraduateSchoolofChineseAcademyofSciences 3.StateKeyLaboratoryofTropicalCropsBiotechnology,InstituteofTropicalBioscienceandBiotechnology,ChineseAcademyofTropicalAgricultureSciences |
| 推荐引用方式 GB/T 7714 | Tian MQ,Dai HF,Li XM,et al. Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris. 2009. |
入库方式： OAI收割
来源：海洋研究所
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