Population genomic analysis reveals a polygenic sex determination system in Apostichopus japonicus
文献类型：期刊论文
| 作者 | Jiang, Chunxi2,3,4,5; Liu, Shilin2,3,4,5; Yang, Yujia6; Cui, Wei2,3,4,5 ; Xu, Shuai2,3,4,5; Rasoamananto, Irene1; Lavitra, Thierry1; Zhang, Libin2,3,4,5; Sun, Lina2,3,4,5
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| 刊名 | ISCIENCE
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| 出版日期 | 2024-10-18 |
| 卷号 | 27期号:10页码:16 |
| DOI | 10.1016/j.isci.2024.110852 |
| 通讯作者 | Sun, Lina(sunlina@qdio.ac.cn) |
| 英文摘要 | The sea cucumber Apostichopus japonicus , , a key species in Chinese aquaculture, plays a significant evolutionary role within the Echinodermata phylum. However, the sex determination mechanism in this species remains poorly understood. Here, we conducted extensive sex surveys and sampling of eight wild populations, investigating the sex-related SNPs and insertion or deletions (indels) through bulk segregation analysis (BSA) and genome-wide association study (GWAS) analysis. Our findings suggest that A. japonicus employs a polygenic sex determination (PSD) system, with solute carrier family 8 (SLC8A) being the candidate gene for sex determination, encoding sodium-calcium exchanger (NCX1). The analysis of normalized sequencing depth reveals variations across chromosomes 6,13,14, 16, and 18, supporting the PSD system. We also identified 541.656 kb of male-specific sequences and screened five markers (C77185, C98086, C64977, C125, and C876) for molecular sex identification. Overall, this study provides new insights into A. japonicus sex determination, highlighting a complex multi-gene mechanism rather than a simple XX/XY system. |
| WOS关键词 | DNA ; CHROMOSOMES |
| 资助项目 | National Key Research and Development Program of China[2022YFE0140900] ; Key Research and Development Program of Shan-dong[2021LZGC029] ; National Natural Science Foundation of China[42206084] ; Taishan Scholars Program[tsqn202306279] |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001320826300001 |
| 出版者 | CELL PRESS |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/199246]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 |
| 通讯作者 | Sun, Lina |
| 作者单位 | 1.Univ Toliara, Inst Halieut & Sci Marines IHSM, Toliara, Madagascar 2.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 3.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao 266237, Peoples R China 4.Chinese Acad Sci, Inst Oceanol, Key Lab Breeding Biotechnol & Sustainable Aquacult, Qingdao 266071, Peoples R China 5.Univ Chinese Acad Sci, Beijing 100049, Peoples R China 6.Ocean Univ China, Key Lab Mariculture, Minist Educ, Qingdao, Peoples R China |
| 推荐引用方式 GB/T 7714 | Jiang, Chunxi,Liu, Shilin,Yang, Yujia,et al. Population genomic analysis reveals a polygenic sex determination system in Apostichopus japonicus[J]. ISCIENCE,2024,27(10):16. |
| APA | Jiang, Chunxi.,Liu, Shilin.,Yang, Yujia.,Cui, Wei.,Xu, Shuai.,...&Sun, Lina.(2024).Population genomic analysis reveals a polygenic sex determination system in Apostichopus japonicus.ISCIENCE,27(10),16. |
| MLA | Jiang, Chunxi,et al."Population genomic analysis reveals a polygenic sex determination system in Apostichopus japonicus".ISCIENCE 27.10(2024):16. |
入库方式： OAI收割
来源：海洋研究所
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