Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci
文献类型：期刊论文
| 作者 | Duan, Zelin2,3,4,5; Wang, Jing2,4,5 ; Liu, Shuya2,4,5; Xu, Qing2,4,5,6; Chen, Hao7; Li, Chaolun2,7; Hui, Min1,2,3; Chen, Nansheng2,3,5,6
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| 刊名 | SCIENCE OF THE TOTAL ENVIRONMENT
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| 出版日期 | 2024-11-10 |
| 卷号 | 950页码:13 |
| 关键词 | Thermocollonia jamsteci Comparative genomics Transposon burst Chromosome evolution Ciliary transport Deep-sea adaptive evolution |
| ISSN号 | 0048-9697 |
| DOI | 10.1016/j.scitotenv.2024.175358 |
| 通讯作者 | Hui, Min(minhui@qdio.ac.cn) ; Chen, Nansheng(chenn@qdio.ac.cn) |
| 英文摘要 | Deep-sea hydrothermal vents are characterized by high hydrostatic pressure, hypoxia, darkness and toxic substances. However, how organisms adapt to such extreme marine ecosystems remain poorly understood. We hypothesize that adaptive evolution plays an essential role in generating novelty for evolutionary adaptation to the deep-sea environment because adaptive evolution has been found to be critical for species origin and evolution. In this project, the chromosome-level genome of the deep-sea hydrothermal vent gastropod T. jamsteci was constructed for the first time to examine molecular mechanisms of its adaptation to the deep-sea environment. The genome size was large (2.54 Gb), ranking at the top of all species in the Vetigastropoda subclass, driven primarily by the bursts of transposable elements (TEs). The transposition of TEs may also trigger chromosomal changes including both inter-chromosomal fusions and intra-chromosomal activities involving chromosome inversions, rearrangements and fusions, as revealed by comparing the genomes of T. jamsteci and its closely related shallow-sea species Gibbula magus. Innovative changes including the expansion of the ABC transporter gene family that may facilitate detoxification, duplication of genes related to endocytosis, immunity, apoptosis, and anti-apoptotic domains that may help T. jamsteci fight against microbial pathogens, were identified. Furthermore, comparative analysis identified positive selection signals in a large number of genes including the hypoxia up-regulated protein 1, which is a chaperone that may promote adaptation of the T. jamsteci to hypoxic deepsea environments, hox2, Rx2, Pax6 and cilia-related genes BBS1, BBS2, BBS9 and RFX4. Notably, because of the critical importance of cilia and IFT in development, positive selection in ciliarelated genes may play a critical role in facilitating T. jamsteci to adapt to the high-pressure deep-sea ecosystem. Results from this study thus revealed important molecular clues that may facilitate further research on the adaptation of molluscs to deep-sea hydrothermal vents. |
| WOS关键词 | JURASSIC MASS EXTINCTION ; GENOME-SIZE VARIATION ; TRANSPOSABLE ELEMENTS ; HOMEOBOX GENE ; EYE ; EVOLUTION ; PROVIDES ; SYSTEM ; INTEGRATION ; EXPRESSION |
| 资助项目 | Science and Technology Innovation Project of Laoshan Laboratory[LSKJ202203100] ; Strategic Priority Research Program of Chinese Academy of Sciences[XDB42000000] ; Taishan Scholar Project Special Fund ; National Natural Science Foundation of China[42030407] ; Marine S & T Fund of Shandong Province for Pilot National Laboratory for Marine Science and Technology (Qingdao)[2022QNLM030004] ; Oceanographic Data Center, IOCAS |
| WOS研究方向 | Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001294309600001 |
| 出版者 | ELSEVIER |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/199594]  |
| 专题 | 海洋研究所_海洋生态与环境科学重点实验室 海洋研究所_海洋生物分类与系统演化实验室 |
| 通讯作者 | Hui, Min; Chen, Nansheng |
| 作者单位 | 1.Chinese Acad Sci, Inst Oceanol, Lab Marine Organism Taxon & Phylogeny, Qingdao Key Lab Marine Biodivers & Conservat, Qingdao 266071, Peoples R China 2.Chinese Acad Sci, Inst Oceanol, CAS Key Lab Marine Ecol & Environm Sci, Qingdao 266071, Peoples R China 3.Laoshan Lab, Qingdao 266237, Peoples R China 4.Qingdao Marine Sci & Technol Ctr, Lab Marine Ecol & Environm Sci, Qingdao, Peoples R China 5.Chinese Acad Sci, Ctr Ocean Mega Sci, Qingdao 266071, Peoples R China 6.China Three Gorges Univ, Coll Basic Med Sci, Yichang 443000, Peoples R China 7.Chinese Acad Sci, Ctr Deep Sea Res, Inst Oceanol, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Duan, Zelin,Wang, Jing,Liu, Shuya,et al. Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci[J]. SCIENCE OF THE TOTAL ENVIRONMENT,2024,950:13. |
| APA | Duan, Zelin.,Wang, Jing.,Liu, Shuya.,Xu, Qing.,Chen, Hao.,...&Chen, Nansheng.(2024).Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci.SCIENCE OF THE TOTAL ENVIRONMENT,950,13. |
| MLA | Duan, Zelin,et al."Positive selection in cilia-related genes may facilitate deep-sea adaptation of Thermocollonia jamsteci".SCIENCE OF THE TOTAL ENVIRONMENT 950(2024):13. |
入库方式： OAI收割
来源：海洋研究所
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