Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
文献类型：期刊论文
| 作者 | He, Jipei4,5; Li, Heng5; Dai, Xiaojiang5; Xie, Zhengyong4; Song, Zhigao3; Chen, Xi4; Huang, Hongyan5; Ding, Yunfa5; Qi, Tengfei5; Liu, Qing2 |
| 刊名 | JOVE-JOURNAL OF VISUALIZED EXPERIMENTS
 |
| 出版日期 | 2024-10-01 |
| 期号 | 212页码:12 |
| ISSN号 | 1940-087X |
| DOI | 10.3791/66049 |
| 通讯作者 | Zhang, Hongbin(zhangwater@hotmail.com) ; Wu, Liangping(drwulp@163.com) |
| 英文摘要 | The prevalence of obesity and type 2 diabetes is a serious global health concern. Obesity is a major pathogenic factor in type 2 diabetes, cardiovascular disease, and some cancers. Bariatric surgery offers a long-term and effective treatment option for both obesity and diabetes. Sleeve gastrectomy (SG) and Roux-en-Y gastric bypass (RYGB) are widely recognized as the most popular bariatric surgeries. Additionally, several exploratory bariatric surgeries have demonstrated promising therapeutic effects. Duodenal-jejunal bypass (DJB), specifically tailored for diabetics with low body mass index, has shown beneficial metabolic outcomes. However, its weightindependent metabolic benefits are not fully understood due to limited animal models. In this article, we describe the optimized care protocols and surgical techniques for performing DJB surgery in diet-induced obese (DIO) diabetic mice. Using a mouse model contributes to a better understanding of the nature of changes induced by DJB surgery while facilitating related clinical practice. |
| WOS关键词 | BARIATRIC SURGERY ; ANIMAL-MODELS ; EVOLUTION |
| 资助项目 | Science and Technology Planning Project of Guangdong Province of China[202002020069] |
| WOS研究方向 | Science & Technology - Other Topics |
| 语种 | 英语 |
| WOS记录号 | WOS:001351598200007 |
| 出版者 | JOURNAL OF VISUALIZED EXPERIMENTS |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/314379]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Zhang, Hongbin; Wu, Liangping |
| 作者单位 | 1.Southern Med Univ, Sch Lab & Biotechnol, Guangzhou, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Zhongshan Inst Drug Discovery, Beijing, Peoples R China 3.Southern Med Univ, Dept Cardiovasc Surg, Zhujiang Hosp, Guangzhou, Peoples R China 4.Gen Hosp Southern Theatre Command, Guangzhou, Peoples R China 5.Guangzhou Univ Chinese Med, Jinshazhou Hosp, Guangzhou, Peoples R China 6.Guangzhou Hualiang Qingying Biotechnol Co Ltd, Guangzhou, Peoples R China |
| 推荐引用方式 GB/T 7714 | He, Jipei,Li, Heng,Dai, Xiaojiang,et al. Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice[J]. JOVE-JOURNAL OF VISUALIZED EXPERIMENTS,2024(212):12. |
| APA | He, Jipei.,Li, Heng.,Dai, Xiaojiang.,Xie, Zhengyong.,Song, Zhigao.,...&Wu, Liangping.(2024).Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice.JOVE-JOURNAL OF VISUALIZED EXPERIMENTS(212),12. |
| MLA | He, Jipei,et al."Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice".JOVE-JOURNAL OF VISUALIZED EXPERIMENTS .212(2024):12. |
入库方式： OAI收割
来源：上海药物研究所
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