The nature of progenitors of Type Ia supernovae (SNe Ia) and their explosion mechanism remains unclear. It has been suggested that SNe Ia may have resulted from thermonuclear explosions of hybrid carbon-oxygen-neon white dwarfs (CONe WDs) when they grow in mass to approach the Chandrasekhar mass limit by accreting matter from a binary main-sequence (MS) companion. In this work, we combine the results of detailed binary evolution calculations with population synthesis models to investigate the rates and delay times of SNe Ia in the CONe WD + MS channel at a low metallicity environment of Z = 0.0001. For a constant star formation rate of 5 M-circle dot yr(-1), our calculations predict that the SN Ia rates in the CONe WD + MS channel at low metallicity of Z = 0.0001 is about 0.11-3.89 x 10(-4) yr(-1). In addition, delay times in this channel cover a wide range of 0.05-2.5 Gyr. We further compare our results to those given by a previous study for the CONe WD + MS channel with a higher metallicity of Z = 0.02 to explore the influence of metallicity on the results. We find that these two metallicity environments give a slight difference in rates and delay times of SNe Ia from the CONe WD + MS channel, although SNe Ia produced at a low metallicity environment of Z = 0.0001 have relatively longer delay times.