中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
New Arylalkenyl α-Pyrones from Cryptocarya densiflora

文献类型:期刊论文

作者Meng, Jie5; Xue, Jun-Juan4; Miao, Lei3; Zhang, Yu3; Rao, Li5; Zhang, Chuan-Rui1,2,3,5
刊名CHEMISTRY & BIODIVERSITY
出版日期2025-01-07
页码6
关键词alpha-pyrones Cryptocarya densiflora cytotoxicity quantum chemical calculations spectroscopic data
ISSN号1612-1872
DOI10.1002/cbdv.202403120
通讯作者Zhang, Chuan-Rui(zhangchuanrui@simm.ac.cn)
英文摘要Four previously undescribed arylalkenyl alpha-pyrones, designated as crydensiones A-D (1-4), were isolated from the twigs and leaves of Cryptocarya densiflora. Their structures were determined through comprehensive spectroscopic analyses together with quantum chemical calculations of electronic circular dichroism and nuclear magnetic resonance data. All isolates were assessed for cytotoxicity against HCT-116 (colon), A549 (lung), and MDA-MB-231 (breast) cancer cell lines; however, none demonstrated significant activity.
WOS关键词INHIBITORY-ACTIVITY ; A-H ; FLAVANONES ; FLAVONOIDS ; ALKALOIDS ; CHINENSIS ; LEAVES
资助项目National Natural Science Foundation of China ; Fund of State Key Laboratory of Phytochemistry and Plant Resources in West China[P2020-KF09] ; [22177016]
WOS研究方向Biochemistry & Molecular Biology ; Chemistry
语种英语
WOS记录号WOS:001390687100001
出版者WILEY-V C H VERLAG GMBH
源URL[http://119.78.100.183/handle/2S10ELR8/315585]  
专题中国科学院上海药物研究所
通讯作者Zhang, Chuan-Rui
作者单位1.Chinese Acad Sci, Kunming Inst Bot, State Key Lab Phytochem & Plant Resources West Chi, Kunming, Peoples R China
2.Chinese Acad Sci, Shanghai Inst Mat Med, Shanghai, Peoples R China
3.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai, Peoples R China
4.Shandong Coll Tradit Chinese Med, Dept Tradit Chinese Med, Yantai, Peoples R China
5.Chongqing Univ, Sch Pharmaceut Sci, Chongqing Key Lab Nat Prod Synth & Drug Res, Chongqing, Peoples R China
推荐引用方式
GB/T 7714
Meng, Jie,Xue, Jun-Juan,Miao, Lei,et al. New Arylalkenyl α-Pyrones from Cryptocarya densiflora[J]. CHEMISTRY & BIODIVERSITY,2025:6.
APA Meng, Jie,Xue, Jun-Juan,Miao, Lei,Zhang, Yu,Rao, Li,&Zhang, Chuan-Rui.(2025).New Arylalkenyl α-Pyrones from Cryptocarya densiflora.CHEMISTRY & BIODIVERSITY,6.
MLA Meng, Jie,et al."New Arylalkenyl α-Pyrones from Cryptocarya densiflora".CHEMISTRY & BIODIVERSITY (2025):6.

入库方式: OAI收割

来源:上海药物研究所

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