Application of lipidomics in the study of traditional Chinese medicine
文献类型：期刊论文
| 作者 | Yang, Yang; Yang, Guangyi3; Zhang, Wenpeng2; Xin, Lingyi3,4; Zhu, Jing3,4; Wang, Hangtian3; Feng, Baodong4; Liu, Renyan4; Zhang, Shuya4; Cui, Yuanwu4 |
| 刊名 | JOURNAL OF PHARMACEUTICAL ANALYSIS
 |
| 出版日期 | 2025-02-01 |
| 卷号 | 15期号:2页码:13 |
| 关键词 | China Lipidomics Traditional Chinese medicine Mechanism Curative effect Toxicity Quality control |
| ISSN号 | 2095-1779 |
| DOI | 10.1016/j.jpha.2024.101083 |
| 通讯作者 | Chen, Qinhua(cqh77@163.com) ; Guo, Dean(daguo@simm.ac.cn) |
| 英文摘要 | Lipidomics is an emerging discipline that systematically studies the various types, functions, and metabolic pathways of lipids within living organisms. This field compares changes in diseases or drug impact, identifying biomarkers and molecular mechanisms present in lipid metabolic networks across different physiological or pathological states. Through employing analytical chemistry within the realm of lipidomics, researchers analyze traditional Chinese medicine (TCM). This analysis aids in uncovering potential mechanisms for treating diverse physiopathological conditions, assessing drug efficacy, understanding mechanisms of action and toxicity, and generating innovative ideas for disease prevention and treatment. This manuscript assesses recent literature, summarizing existing lipidomics technologies and their applications in TCM research. It delineates the efficacy, mechanisms, and toxicity research related to lipidomics in Chinese medicine. Additionally, it explores the utilization of lipidomics in quality control research for Chinese medicine, aiming to expand the application of lipidomics within this field. Ultimately, this initiative seeks to foster the integration of traditional medicine theory with modern science and technology, promoting an organic fusion between the two domains. (c) 2024 The Author(s). Published by Elsevier B.V. on behalf of Xi'an Jiaotong University. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
| WOS关键词 | ION MOBILITY SPECTROMETRY ; COLLISION CROSS-SECTION ; SOLID-PHASE EXTRACTION ; MASS-SPECTROMETRY ; LIQUID-CHROMATOGRAPHY ; HIGH-THROUGHPUT ; PROFILING REVEALS ; FATTY-ACIDS ; CRUDE EXTRACTS ; LIPIDS |
| WOS研究方向 | Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001424628800001 |
| 出版者 | ELSEVIER |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/316299]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Chen, Qinhua; Guo, Dean |
| 作者单位 | 1.Chinese Acad Sci, Shanghai Inst Mat Med, Lab TCM Standardizat Technol, Shanghai 201203, Peoples R China 2.Tsinghua Univ, Dept Precis Instrument, State Key Lab Precis Measurement Technol & Instrum, Beijing 100084, Peoples R China 3.Shenzhen Hosp Integrated Tradit Chinese & Western, Dept Pharm, Shenzhen 518000, Guangdong, Peoples R China 4.Shenzhen Baoan Authent TCM Therapy Hosp, Key Lab TCM Clin Pharm, Shenzhen 518000, Guangdong, Peoples R China |
| 推荐引用方式 GB/T 7714 | Yang, Yang,Yang, Guangyi,Zhang, Wenpeng,et al. Application of lipidomics in the study of traditional Chinese medicine[J]. JOURNAL OF PHARMACEUTICAL ANALYSIS,2025,15(2):13. |
| APA | Yang, Yang.,Yang, Guangyi.,Zhang, Wenpeng.,Xin, Lingyi.,Zhu, Jing.,...&Guo, Dean.(2025).Application of lipidomics in the study of traditional Chinese medicine.JOURNAL OF PHARMACEUTICAL ANALYSIS,15(2),13. |
| MLA | Yang, Yang,et al."Application of lipidomics in the study of traditional Chinese medicine".JOURNAL OF PHARMACEUTICAL ANALYSIS 15.2(2025):13. |
入库方式： OAI收割
来源：上海药物研究所
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