Total synthesis of cyclopropane-containing natural products: recent progress (2016-2024)
文献类型：期刊论文
| 作者 | Wang, Neng2; Zhao, Jin-Xin1,2; Yue, Jian-Min1,2
|
| 刊名 | ORGANIC CHEMISTRY FRONTIERS
 |
| 出版日期 | 2025-01-24 |
| 页码 | 18 |
| ISSN号 | 2052-4129 |
| DOI | 10.1039/d4qo02316a |
| 英文摘要 | Cyclopropane, as the smallest all-carbon ring, is a ubiquitous functional group found in many complex natural products, such as terpenoids, alkaloids, steroids, and fatty acids. Natural products containing cyclopropane motifs have attracted burgeoning interest owing to their fascinating architectural features and versatile biological properties. In recent decades, a variety of methods for the construction of cyclopropane rings have emerged, which can be mainly classified into [2 + 1]-type cycloaddition and direct 1,3-cyclization. These methods have been extensively utilized by synthetic chemists in their pursuit of synthesizing cyclopropane-containing natural products. This review outlines recent progress in this research area, with a particular focus on the ingenious application of novel synthetic methodologies and tactics for assembling naturally occurring three-membered rings, aiming to complement the existing literature in this field. |
| WOS关键词 | DI-PI-METHANE ; TIGLIANE DITERPENOIDS ; SKELETON ; GOLD ; BIOSYNTHESIS ; CONSTRUCTION ; ALKALOIDS ; OLEFINS ; FE |
| 资助项目 | National Natural Science Foundation of China[2023YFE0206100] ; National Key Research and Development Program of China[82404459] ; National Natural Science Foundation of China[2022282] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences (CAS)[SIMM0120231001] ; Youth Innovation Promotion Association of the Chinese Academy of Sciences (CAS)[SIMM0120231002] ; Shanghai Institute of Materia Medica of CAS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001411117200001 |
| 出版者 | ROYAL SOC CHEMISTRY |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/315974]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Yue, Jian-Min |
| 作者单位 | 1.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, 198 East Binhai Rd, Yantai 264117, Shandong, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, Ethnomed & Biofunct Mol Res Ctr, State Key Lab Drug Res, 555 Zuchongzhi Rd, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Neng,Zhao, Jin-Xin,Yue, Jian-Min. Total synthesis of cyclopropane-containing natural products: recent progress (2016-2024)[J]. ORGANIC CHEMISTRY FRONTIERS,2025:18. |
| APA | Wang, Neng,Zhao, Jin-Xin,&Yue, Jian-Min.(2025).Total synthesis of cyclopropane-containing natural products: recent progress (2016-2024).ORGANIC CHEMISTRY FRONTIERS,18. |
| MLA | Wang, Neng,et al."Total synthesis of cyclopropane-containing natural products: recent progress (2016-2024)".ORGANIC CHEMISTRY FRONTIERS (2025):18. |
入库方式： OAI收割
来源：上海药物研究所
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