Solid phase synthesis of molecularly imprinted polymers for analytical and life science applications
文献类型：期刊论文
| 作者 | Muhammad, Turghun1; Zhao, Danni1; Guerreiro, Antonio2; Muhammad, Imran1; Aimaitiniyazi, Munire1; Ding, Bei1; Zheng, Yue1; Yimamumaimaiti, Tajiguli1; Chen, Lingxin3; Piletsky, Sergey A.4 |
| 刊名 | TRAC-TRENDS IN ANALYTICAL CHEMISTRY
 |
| 出版日期 | 2025-03-01 |
| 卷号 | 184页码:21 |
| 关键词 | Solid-phase synthesis Molecularly imprinted polymer Optical analysis Electrochemical analysis Future perspectives |
| ISSN号 | 0165-9936 |
| DOI | 10.1016/j.trac.2025.118134 |
| 通讯作者 | Muhammad, Turghun(turghunm@xju.edu.cn) |
| 英文摘要 | Molecularly imprinted polymers are highly valued in diverse fields due to their overall stability, molecular recognition capabilities, and low-cost of preparation. Solid-phase synthesis has been an important imprinting strategy developed in the past decade. Distinct from conventional imprinting methods, the solid-phase synthesis approach immobilizes the template molecules onto the substrate. The immobilization of template molecules not only avoids the leakage of template molecules but also enables the reuse of template molecules and improving specificity of polymer binding sites. During preparation, low-affinity molecularly imprinted polymer nanoparticles (nanoMIPs) can be separated while high affinity nanoMIPs are subsequently collected. Remarkably, nanoMIPs have demonstrated comparable or even superior performance to biological antibodies in diverse biomedical and trace detection applications. This comprehensive review covers the whole process of preparation, characterization, and application of nanoMIPs synthesized through the solid-phase synthesis. Furthermore, it provides an analysis of the status of the technique and a discussion on future development. |
| WOS关键词 | SURFACE-PLASMON RESONANCE ; THERMAL DETECTION ; BINDING-SITES ; NANOPARTICLES ; AFFINITY ; RECOGNITION ; ASSAY ; ELISA ; MIP ; RECEPTORS |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001398601900001 |
| 资助机构 | National Natural Science Foundation of China ; Fujian Natural Science Foun-dation |
| 源URL | [http://ir.yic.ac.cn/handle/133337/40397]  |
| 专题 | 烟台海岸带研究所_中科院海岸带环境过程与生态修复重点实验室 烟台海岸带研究所_山东省海岸带环境工程技术研究中心 |
| 通讯作者 | Muhammad, Turghun |
| 作者单位 | 1.Xinjiang Univ, Coll Chem, State Key Lab Chem & Utilizat Carbon Based Energy, Urumqi 830017, Peoples R China 2.MIP Diagnost, Leicester, England 3.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Res Ctr Coastal Environm Engn & Technol, CAS Key Lab Coastal Environm Proc & Ecol Remediat, Yantai 264003, Peoples R China 4.Univ Leicester, Chem Dept, Coll Sci & Engn, Leicester LE1 7RH, England |
| 推荐引用方式 GB/T 7714 | Muhammad, Turghun,Zhao, Danni,Guerreiro, Antonio,et al. Solid phase synthesis of molecularly imprinted polymers for analytical and life science applications[J]. TRAC-TRENDS IN ANALYTICAL CHEMISTRY,2025,184:21. |
| APA | Muhammad, Turghun.,Zhao, Danni.,Guerreiro, Antonio.,Muhammad, Imran.,Aimaitiniyazi, Munire.,...&Piletsky, Sergey A..(2025).Solid phase synthesis of molecularly imprinted polymers for analytical and life science applications.TRAC-TRENDS IN ANALYTICAL CHEMISTRY,184,21. |
| MLA | Muhammad, Turghun,et al."Solid phase synthesis of molecularly imprinted polymers for analytical and life science applications".TRAC-TRENDS IN ANALYTICAL CHEMISTRY 184(2025):21. |
入库方式： OAI收割
来源：烟台海岸带研究所
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