Marine mussel metabolism under stress: Dual effects of nanoplastics and coastal hypoxia
文献类型：期刊论文
| 作者 | Wang, Xin1,2; Zhang, Tianyu1,2; Yang, Dinglong1,2; Xu, Elvis Genbo3; Javidpour, Jamileh3; Zhao, Jianmin1,2,4 |
| 刊名 | JOURNAL OF HAZARDOUS MATERIALS
 |
| 出版日期 | 2025-03-05 |
| 卷号 | 485页码:11 |
| 关键词 | Nanoplastics Hypoxia Metabolomics Multiple stresses Mytilus galloprovincialis |
| ISSN号 | 0304-3894 |
| DOI | 10.1016/j.jhazmat.2024.136860 |
| 通讯作者 | Xu, Elvis Genbo(elvis@biology.sdu.dk) ; Zhao, Jianmin(jmzhao@yic.ac.cn) |
| 英文摘要 | Emerging challenges in marine environments include nanoplastics (NPs) pollution and coastal hypoxia. Although NPs toxicity in marine organisms is being increasingly documented, the complex interactions between coastal hypoxia and NPs remain largely unexplored. This study investigated the dual effects of polystyrene nanoplastics and different oxygen levels on redox homeostasis and bioenergetics in the marine model organism Mytilus galloprovincialis. Both NPs and hypoxia significantly disrupted redox homeostasis in mussels. Exposure to NPs alone increased electron transport chain activity, whereas exposure to hypoxia alone and co-exposure significantly reduced this activity. Metabolomic analysis showed that NPs primarily affected the pentose phosphate pathway (PPP), tricarboxylic acid (TCA) cycle, and amino acid metabolism; hypoxia exposure alone disrupted the TCA cycle, pyruvate metabolism, and glycolysis/gluconeogenesis, whereas combined exposure notably altered the TCA cycle, PPP, and sugar interconversion. This suggests that regulating these pathways would help mussels cope with the combined environmental stress. Furthermore, co-exposure severely disrupted redox homeostasis and energy metabolism in mussels, suggesting that hypoxia exacerbates NPs toxicity. We believe that these new findings would enhance our understanding of the compounded ecological risks posed by NPs in the context of climate change. |
| WOS关键词 | BIVALVE MYTILUS-GALLOPROVINCIALIS ; OXIDATIVE-STRESS ; LIFE-SPAN ; HEXOKINASE ; MICROPLASTICS ; COMPLEX ; NANOPARTICLES ; MITOCHONDRIA ; RESPIRATION ; GLUTATHIONE |
| WOS研究方向 | Engineering ; Environmental Sciences & Ecology |
| 语种 | 英语 |
| WOS记录号 | WOS:001388297200001 |
| 资助机构 | National Science & Technology Fundamental Resources Investigation Program of China ; Youth Innovation Promotion Association, Chinese Academy of Sciences ; Seed Project of Yantai Institute of Coastal Zone Research, Chinese Academy of Sciences ; Department of Biology, University of Southern Denmark ; Danmarks Frie Forskningsfond |
| 源URL | [http://ir.yic.ac.cn/handle/133337/40268]  |
| 专题 | 海岸带生物学与生物资源利用重点实验室 海岸带生物资源高效利用研究与发展中心 |
| 通讯作者 | Xu, Elvis Genbo; Zhao, Jianmin |
| 作者单位 | 1.Chinese Acad Sci, Key Lab Coastal Biol & Biol Resource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China 2.Chinese Acad Sci, Yantai Inst Coastal Zone Res, Muping Coastal Environm Res Stn, Yantai 264003, Shandong, Peoples R China 3.Univ Southern Denmark, Dept Biol, DK-5230 Odense, Denmark 4.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Xin,Zhang, Tianyu,Yang, Dinglong,et al. Marine mussel metabolism under stress: Dual effects of nanoplastics and coastal hypoxia[J]. JOURNAL OF HAZARDOUS MATERIALS,2025,485:11. |
| APA | Wang, Xin,Zhang, Tianyu,Yang, Dinglong,Xu, Elvis Genbo,Javidpour, Jamileh,&Zhao, Jianmin.(2025).Marine mussel metabolism under stress: Dual effects of nanoplastics and coastal hypoxia.JOURNAL OF HAZARDOUS MATERIALS,485,11. |
| MLA | Wang, Xin,et al."Marine mussel metabolism under stress: Dual effects of nanoplastics and coastal hypoxia".JOURNAL OF HAZARDOUS MATERIALS 485(2025):11. |
入库方式： OAI收割
来源：烟台海岸带研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。