中国科学院机构知识库网格
Chinese Academy of Sciences Institutional Repositories Grid
首页 机构 成果 学者
  
  1. CAS IR Grid
  2. 烟台海岸带研究所
  3. 中国科学院烟台海岸带研究所
  4. 海岸带生物学与生物资源利用重点实验室
Preparation of novel thiolated chitosan with significant antioxidant activity

文献类型：期刊论文

作者Han, Xiangru1,3; Tian, Liguang4; Chen, Qiuhong2; Wang, Linqing1,3; Mi, Yingqi1,3; Li, Qing1,3; Guo, Zhanyong1,2; Dong, Fang1,3
刊名INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
出版日期2025-05-01
卷号308页码:15
关键词Antioxidant activity Chemical modification Chitosan derivative Thiol group
ISSN号0141-8130
DOI10.1016/j.ijbiomac.2025.142536
通讯作者Guo, Zhanyong(zhanyongguo@hotmail.com) ; Dong, Fang(fdong@yic.ac.cn)
英文摘要The aim of this study was to synthesize thiolated chitosan derivative and evaluated its antioxidant activity. Thiol groups were introduced into chitosan and hydroxypropyl trimethylammonium chloride chitosan quaternary ammonium salt (HACC) by microwave reaction, respectively. At the same time, a series of compounds containing thiol groups were introduced at the amino site. The structure of the chitosan derivatives was identified by FTIR and 1H NMR. The thiol groups content, thermal stability, water solubility and cytotoxicity of the chitosan derivative were evaluated. The antioxidant activity of chitosan derivatives was evaluated using superoxide anion radical scavenging activity assay, DPPH radical scavenging activity assay, hydroxyl radical scavenging activity assay and reducing power assay. The results showed that the thiolated chitosan derivatives obtained in this study possessed excellent antioxidant activity, which provides a new idea for the further study of chitosan antioxidants.
WOS关键词FUNCTIONALIZED CHITOSAN ; GENERATION ; HYDROGELS ; CYSTEINE ; THIOMER
WOS研究方向Biochemistry & Molecular Biology ; Chemistry ; Polymer Science
语种英语
WOS记录号WOS:001462314600001
资助机构Natural Science Foundation of Shandong Province of China ; Chinese Academy of Sciences, Shandong Key R D Plan ; Major Scientific and Technological Innovation Project ; China Postdoctoral Science Foundation ; Natural Science Foundation of Shandong Province ; Central Guiding Local Science and Technology Development Fund Project in Shandong Province
源URL[http://ir.yic.ac.cn/handle/133337/40481]  
专题海岸带生物学与生物资源利用重点实验室
海岸带生物资源高效利用研究与发展中心
通讯作者Guo, Zhanyong; Dong, Fang
作者单位1.Chinese Acad Sci, Key Lab Coastal Biol & Bioresource Utilizat, Yantai Inst Coastal Zone Res, Yantai 264003, Peoples R China
2.Jiangsu Ocean Univ, Coll Marine Sci & Fisheries, Lianyungang 222005, Jiangsu, Peoples R China
3.Univ Chinese Acad Sci, Beijing 100049, Peoples R China
4.Yantai Agr Technol Extens Ctr, Yantai 264003, Peoples R China
推荐引用方式
GB/T 7714		 Han, Xiangru,Tian, Liguang,Chen, Qiuhong,et al. Preparation of novel thiolated chitosan with significant antioxidant activity[J]. INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,2025,308:15.
APA Han, Xiangru.,Tian, Liguang.,Chen, Qiuhong.,Wang, Linqing.,Mi, Yingqi.,...&Dong, Fang.(2025).Preparation of novel thiolated chitosan with significant antioxidant activity.INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES,308,15.
MLA Han, Xiangru,et al."Preparation of novel thiolated chitosan with significant antioxidant activity".INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 308(2025):15.

入库方式： OAI收割

来源：烟台海岸带研究所

浏览0
下载0
收藏0
其他版本

除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。