Alpinoblonoids A and B, Two 16-nor-Labdane-Related Diterpenoids with a Tricyclic Carbon Skeleton from Alpinia oblongifolia
文献类型：期刊论文
| 作者 | Zhang, Bai-Hui1,3; Gan, Lu2; Wu, Yu-Wei1,3; Li, Wen-Xian1; Guo, Dean1,3 ; Li, Wei1,3
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| 刊名 | ORGANIC LETTERS
 |
| 出版日期 | 2025-03-06 |
| 卷号 | 27期号:10页码:2504-2508 |
| ISSN号 | 1523-7060 |
| DOI | 10.1021/acs.orglett.5c00574 |
| 通讯作者 | Guo, Dean(daguo@simm.ac.cn) ; Li, Wei(liwei1@simm.ac.cn) |
| 英文摘要 | Alpinoblonoids A (1) and B (2), two 16-nor-labdane related diterpenoids featuring 2,6,6,10,11-pentamethyltricyclo[8.4.0.02,7]tetradecane and 11-ethyl-2,6,6,10-tetramethyltricyclo[8.3.0.02,7]tridecane skeletons, respectively, along with their biosynthetic precursor (3), were isolated from the rhizomes of Alpinia oblongifolia. Their structural elucidation was achieved by a variety of techniques, including spectroscopic and chemical methods, ECD calculations, as well as single-crystal X-ray diffraction. Compounds 1 and 2 exhibited antihepatic fibrosis activity by inhibiting the expressions of fibronectin, collagen I, and alpha-smooth muscle actin. |
| WOS关键词 | LABDANE DITERPENOIDS |
| 资助项目 | National Natural Science Foundation of China[82104020] ; National Natural Science Foundation of China |
| WOS研究方向 | Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001438747200001 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/316529]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Guo, Dean; Li, Wei |
| 作者单位 | 1.Chinese Acad Sci, Zhongshan Inst Drug Discovery, Shanghai Inst Mat Med, Zhongshan 528400, Peoples R China 2.Sun Yat Sen Univ, Sch Pharmaceut Sci, Guangzhou 510006, Peoples R China 3.Southern Med Univ, Sch Pharmaceut Sci, Guangzhou 510515, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhang, Bai-Hui,Gan, Lu,Wu, Yu-Wei,et al. Alpinoblonoids A and B, Two 16-nor-Labdane-Related Diterpenoids with a Tricyclic Carbon Skeleton from Alpinia oblongifolia[J]. ORGANIC LETTERS,2025,27(10):2504-2508. |
| APA | Zhang, Bai-Hui,Gan, Lu,Wu, Yu-Wei,Li, Wen-Xian,Guo, Dean,&Li, Wei.(2025).Alpinoblonoids A and B, Two 16-nor-Labdane-Related Diterpenoids with a Tricyclic Carbon Skeleton from Alpinia oblongifolia.ORGANIC LETTERS,27(10),2504-2508. |
| MLA | Zhang, Bai-Hui,et al."Alpinoblonoids A and B, Two 16-nor-Labdane-Related Diterpenoids with a Tricyclic Carbon Skeleton from Alpinia oblongifolia".ORGANIC LETTERS 27.10(2025):2504-2508. |
入库方式： OAI收割
来源：上海药物研究所
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