Phomaligol J, a New Cyclohexenone With Antibacterial Activity From a Pufferfish-Associated Fungus Aspergillus austwickii
文献类型：期刊论文
| 作者 | Du, Wang-Yang2,3; Wang, Hui-Fang1,3; Sun, Ruo-Nan3,4; Jin, Yang3,4; Wang, Hai-Feng1; Ma, Chao2; Li, Xu-Wen3,4
|
| 刊名 | CHEMISTRY & BIODIVERSITY
 |
| 出版日期 | 2025-03-20 |
| 页码 | 6 |
| 关键词 | antibacterial activity
|
| ISSN号 | 1612-1872 |
| DOI | 10.1002/cbdv.202500503 |
| 通讯作者 | Ma, Chao(machao_syphu@163.com) ; Li, Xu-Wen(xwli@simm.ac.cn) |
| 英文摘要 | A new cyclohexenone, phomaligol J (1), along with nine known compounds (2-10) were isolated from the liquid culture of the pufferfish-associated Aspergillus austwickii collected from Yangma Island, Yantai. Their structures were determined by extensive spectroscopic data analysis, high resolution electrospray ionization mass spectrometry (HRESIMS), electronic circular dichroism (ECD), and the comparison with reported data in the literature. In bioactivity, all isolated compounds were evaluated for antibacterial activity against 12 bacterial strains. Notably, compound 1 exhibited moderate antibacterial activity against Staphylococcus aureus with a minimum inhibitory concentration (MIC) value of 40 mu g/mL. |
| WOS关键词 | PRODUCT |
| 资助项目 | National Key Research and Development Program of China[2021YFF0502400] ; Shandong Laboratory Program[SYS202205] ; Taishan Scholars Program[tsqn202312302] ; Fundamental Research Projects of Science & Technology Innovation and Development Plan in Yantai City[2023JCYJ057] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001448139200001 |
| 出版者 | WILEY-V C H VERLAG GMBH |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/316692]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Ma, Chao; Li, Xu-Wen |
| 作者单位 | 1.Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang, Peoples R China 2.Shenyang Pharmaceut Univ, Sch Pharmaceut Engn, Key Lab Struct Based Drug Design & Discovery, Minist Educ, Shenyang, Peoples R China 3.Bohai Rim Adv Res Inst Drug Discovery, Shandong Lab Yantai Drug Discovery, Yantai, Shandong, Peoples R China 4.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Chem Biol, Shanghai, Peoples R China |
| 推荐引用方式 GB/T 7714 | Du, Wang-Yang,Wang, Hui-Fang,Sun, Ruo-Nan,et al. Phomaligol J, a New Cyclohexenone With Antibacterial Activity From a Pufferfish-Associated Fungus Aspergillus austwickii[J]. CHEMISTRY & BIODIVERSITY,2025:6. |
| APA | Du, Wang-Yang.,Wang, Hui-Fang.,Sun, Ruo-Nan.,Jin, Yang.,Wang, Hai-Feng.,...&Li, Xu-Wen.(2025).Phomaligol J, a New Cyclohexenone With Antibacterial Activity From a Pufferfish-Associated Fungus Aspergillus austwickii.CHEMISTRY & BIODIVERSITY,6. |
| MLA | Du, Wang-Yang,et al."Phomaligol J, a New Cyclohexenone With Antibacterial Activity From a Pufferfish-Associated Fungus Aspergillus austwickii".CHEMISTRY & BIODIVERSITY (2025):6. |
入库方式： OAI收割
来源：上海药物研究所
浏览0
下载0
收藏0
其他版本
除非特别说明，本系统中所有内容都受版权保护，并保留所有权利。