Metabolomic Profiles and Differential Constituents of Andrographis paniculata (Burm. f.) in Different Growth Stages and Parts
文献类型：期刊论文
| 作者 | Hu, Enming1,2,4; Cheng, Rui1; Liu, Annian1; Wang, Ya1; Long, Huali3; Hou, Jinjun3 ; Wang, Daoping2,4; Wu, Wanying3; Wu, Xingdong1,3,4
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| 刊名 | MOLECULES
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| 出版日期 | 2025-03-27 |
| 卷号 | 30期号:7页码:15 |
| 关键词 | |
| DOI | 10.3390/molecules30071490 |
| 通讯作者 | Wu, Wanying(wanyingwu@simm.ac.cn) ; Wu, Xingdong(wuxingdong@zmu.edu.cn) |
| 英文摘要 | Andrographis paniculata (Burm. f.) and its products have a long history of medicinal use in Asia. A. paniculata products are mainly made from the root extraction of stems, leaves and parts, but there may be differences in the proportion of different parts and different harvest times, which ultimately leads to certain differences in product quality. In this study, the chemical components and non-targeted metabolomics were characterized, and the characteristic compounds in different parts of A. paniculata at various growth stages were analyzed. By utilizing polygonal mass defect filtering, precursor ion lists, and a self-built compound library, a total of 225 components were identified in A. paniculata. Notably, spermidine derivatives and phosphatidylcholines were reported for the first time in this plant species. In total, 41 differential components were identified in different parts of A. paniculata. These findings provide scientific evidence for the selection of quality markers in A. paniculata and its products. |
| WOS关键词 | 4-DIMENSIONAL SEPARATION ; MASS-SPECTROMETRY ; MULTICOMPONENTS ; LEAVES ; TIME |
| 资助项目 | National Nature Science Foundation of China ; Department of Science and Technology of Guizhou Province[[2021]420] ; Department of Science and Technology of Guizhou Province[[2023]024] ; Guizhou Engineering Research Center of Industrial Key-technology for Dendrobium Nobile[[2022]048] ; Administration of Traditional Chinese Medicine of Guizhou Province[362 QZYY-2024-197] ; [82160812] ; [82304450] |
| WOS研究方向 | Biochemistry & Molecular Biology ; Chemistry |
| 语种 | 英语 |
| WOS记录号 | WOS:001463927600001 |
| 出版者 | MDPI |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/316998]  |
| 专题 | 中国科学院上海药物研究所 |
| 通讯作者 | Wu, Wanying; Wu, Xingdong |
| 作者单位 | 1.Zunyi Med Univ, Guizhou Engn Res Ctr Ind Key Technol Dendrobium No, Joint Int Res Lab Ethnomed, Minist Educ, Zunyi 563000, Peoples R China 2.Nat Prod Res Ctr Guizhou Prov, Guiyang 550014, Peoples R China 3.Chinese Acad Sci, Shanghai Inst Mat Med, Natl Engn Res Ctr TCM Standardizat Technol, Shanghai 201203, Peoples R China 4.State Key Lab Discovery & Utilizat Funct Component, Guiyang 550014, Peoples R China |
| 推荐引用方式 GB/T 7714 | Hu, Enming,Cheng, Rui,Liu, Annian,et al. Metabolomic Profiles and Differential Constituents of Andrographis paniculata (Burm. f.) in Different Growth Stages and Parts[J]. MOLECULES,2025,30(7):15. |
| APA | Hu, Enming.,Cheng, Rui.,Liu, Annian.,Wang, Ya.,Long, Huali.,...&Wu, Xingdong.(2025).Metabolomic Profiles and Differential Constituents of Andrographis paniculata (Burm. f.) in Different Growth Stages and Parts.MOLECULES,30(7),15. |
| MLA | Hu, Enming,et al."Metabolomic Profiles and Differential Constituents of Andrographis paniculata (Burm. f.) in Different Growth Stages and Parts".MOLECULES 30.7(2025):15. |
入库方式： OAI收割
来源：上海药物研究所
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