Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris
文献类型：期刊论文
| 作者 | Zhu, Xu-Xin1; Fan, Yao-Yue2; Zheng, Cheng-Yu2; Yang, Hong-Ying1; Gao, Kun1; Yue, Jian-Min1,2
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| 刊名 | JOURNAL OF NATURAL PRODUCTS
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| 出版日期 | 2025-03-14 |
| 卷号 | 88期号:3页码:815-820 |
| ISSN号 | 0163-3864 |
| DOI | 10.1021/acs.jnatprod.5c00027 |
| 英文摘要 | Five complex indoline alkaloids, alstolarsines A-E (1-5) possessing two unprecedented carbon skeletons of 6/5/5/7/6/6(5) fused polycyclic systems, were isolated from Alstonia scholaris. Their structures were characterized using various methods including spectroscopic data, ECD spectra, and single-crystal X-ray diffraction. The inhibitory activities of alstolarsines A-D (1-4) on DRAK2 phosphorylation and ATP-citrate lyase were evaluated, but all of them were inactive. |
| WOS关键词 | LEAVES |
| 资助项目 | National Natural Science Foundation of China[21532007] ; National Natural Science Foundation of China[21772213] ; National Natural Science Foundation of China[2018ZX09711001-001-005] ; Drug Innovation Major Project of China[ZSTH-032] ; CAS[19QA1410800] ; Shanghai Rising-Star program Foundation (SCST) |
| WOS研究方向 | Plant Sciences ; Pharmacology & Pharmacy |
| 语种 | 英语 |
| WOS记录号 | WOS:001445757000001 |
| 出版者 | AMER CHEMICAL SOC |
| 源URL | [http://119.78.100.183/handle/2S10ELR8/316671]  |
| 专题 | 新药研究国家重点实验室 |
| 通讯作者 | Gao, Kun; Yue, Jian-Min |
| 作者单位 | 1.Lanzhou Univ, Coll Chem & Chem Engn, State Key Lab Appl Organ Chem, Lanzhou 730000, Peoples R China 2.Chinese Acad Sci, Shanghai Inst Mat Med, State Key Lab Drug Res, Shanghai 201203, Peoples R China |
| 推荐引用方式 GB/T 7714 | Zhu, Xu-Xin,Fan, Yao-Yue,Zheng, Cheng-Yu,et al. Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris[J]. JOURNAL OF NATURAL PRODUCTS,2025,88(3):815-820. |
| APA | Zhu, Xu-Xin,Fan, Yao-Yue,Zheng, Cheng-Yu,Yang, Hong-Ying,Gao, Kun,&Yue, Jian-Min.(2025).Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris.JOURNAL OF NATURAL PRODUCTS,88(3),815-820. |
| MLA | Zhu, Xu-Xin,et al."Alstolarsines A-E, Indoline Alkaloids with Two Different Carbon Skeletons from Alstonia scholaris".JOURNAL OF NATURAL PRODUCTS 88.3(2025):815-820. |
入库方式： OAI收割
来源：上海药物研究所
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