Southeast Tibet is characterized by extensive alpine glaciers and deep valleys, making it highly prone to cryospheric disasters such as avalanches, ice/ice-rock avalanches, glacial lake outburst floods, debris flows, and barrier lakes, which pose severe threats to infrastructure and human safety. Understanding how cryospheric disasters respond to climate warming remains a critical challenge. Using 3.3 km resolution meteorological downscaling data, this study analyzes the spatiotemporal evolution of multiple climate indicators from 1979 to 2022 and assesses their impacts on cryospheric disaster occurrence. The results reveal a significant warming trend across Southeast Tibet, with faster warming in glacier-covered regions. Precipitation generally decreases, though the semi-arid northwest experiences localized increases. Snowfall declines, with the steepest decrease observed around the lower reaches of the Yarlung Zangbo River. In the moisture corridor of the lower reaches of the Yarlung Zangbo River, warming intensifies freeze-thaw cycles, combined with high baseline extreme daily precipitation, which increases the likelihood of glacial disaster chains. In northwestern Southeast Tibet, accelerated glacier melting due to warming, coupled with increasing extreme precipitation, heightens glacial disaster probabilities. While long-term snowfall decline may reduce avalanches, high baseline extreme snowfall suggests short-term threats remain. Finally, this study establishes meteorological indicators for predicting changes in cryospheric disaster risks under climate change.