Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)
文献类型：期刊论文
| 作者 | Wang, Shen-Tong3,5,6; Yang, Qi5; Liu, Ming-Kun1,3,5; Li, Li1,3,5,6,7; Wang, Wei3,5,6; Zhang, Shou-Du2; Zhang, Guo-Fan1,3,4,5,7 |
| 刊名 | ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
 |
| 出版日期 | 2025-06-01 |
| 卷号 | 297页码:12 |
| 关键词 | Front-loading Ion channel Ocean and coastal acidification Oyster Resilience Translational control |
| ISSN号 | 0147-6513 |
| DOI | 10.1016/j.ecoenv.2025.118210 |
| 通讯作者 | Li, Li(lili@qdio.ac.cn) ; Zhang, Shou-Du(shouduzhang@163.com) |
| 英文摘要 | Ocean and coastal acidification (OCA) poses a significant and rapidly emerging threat to mollusks. The physiological resilience of mollusks to OCA varies considerably; however, the underlying molecular mechanisms remain poorly understood. Seawater in estuaries, being more susceptible to acidification than that in open coastal zones, may enhance the tolerance of resident mollusks to low pH levels. Here, we conducted a comparative analysis between estuarine oysters (Crassostrea ariakensis) and Pacific oysters (Crassostrea gigas) using physiological phenotype and transcriptomic analyses to reveal differential acid-tolerance mechanisms in response to constant pH of 7.8. Our findings indicated that survival and respiration rates of C. ariakensis, which inhabits estuaries with fluctuating pH levels, were higher than those of C. gigas, which inhabits open coastal zones with relative stable pH conditions. Acid-responsive genes identified in C. gigas, including molecular chaperones and immune-related genes, exhibited higher constitutive expression in C. ariakensis under control conditions. Co-expression analyses revealed that C. ariakensis mitigated the effects of low pH by expressing genes involved in ion transporter activity and translation control. C. gigas activated genes associated with glycolipid metabolism while inhibiting cell division during acid stress. These findings suggested that C. ariakensis has evolved into a more energy-efficient regulatory network than C. gigas, incorporating both front-loading and responsive mechanisms to maintain acid-base homeostasis. This study is the first to investigate acid-tolerance differences between mollusks inhabiting estuarine and open coastal environments and provides critical insights into the resilience of mollusks in increasingly acidified oceans. |
| WOS关键词 | OCEAN ACIDIFICATION ; CLIMATE-CHANGE ; LOW PH ; RNA ; IMPACTS ; STRESS ; CYTOSKELETON ; ANALOGS |
| 资助项目 | National Natural Science Foundation of China[42406096] ; National Key Research and Development Program of China[2023YFD2401102] ; Key Research and Development Program of Shandong[ZFJH202309] ; Key Research and Development Program of Shandong[2024LZGCQY003] ; Key Research and Development Program of Shandong[2022LZGC015] ; China Agriculture Research System of MOF and MARA[CARS-49] |
| WOS研究方向 | Environmental Sciences & Ecology ; Toxicology |
| 语种 | 英语 |
| WOS记录号 | WOS:001479383000001 |
| 出版者 | ACADEMIC PRESS INC ELSEVIER SCIENCE |
| 源URL | [http://ir.qdio.ac.cn/handle/337002/201778]  |
| 专题 | 海洋研究所_实验海洋生物学重点实验室 |
| 通讯作者 | Li, Li; Zhang, Shou-Du |
| 作者单位 | 1.Shandong Ctr Technol Innovat Oyster Seed Ind, Qingdao, Peoples R China 2.Marine Sci Res Inst Shandong Prov, Qingdao, Shandong, Peoples R China 3.Natl & Local Joint Engn Lab Ecol Mariculture, Qingdao 266071, Peoples R China 4.Qingdao Marine Sci & Technol Ctr, Lab Marine Biol & Biotechnol, Qingdao 266237, Peoples R China 5.Chinese Acad Sci, Inst Oceanol, Shandong Prov Key Lab Expt Marine Biol, Qingdao, Peoples R China 6.Qingdao Marine Sci & Technol Ctr, Lab Marine Fisheries Sci & Food Prod Proc, Qingdao 266237, Peoples R China 7.Chinese Acad Sci, Inst Oceanol, Key Lab Breeding Biotechnol & Sustainable Aquacult, Qingdao 266071, Peoples R China |
| 推荐引用方式 GB/T 7714 | Wang, Shen-Tong,Yang, Qi,Liu, Ming-Kun,et al. Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)[J]. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,2025,297:12. |
| APA | Wang, Shen-Tong.,Yang, Qi.,Liu, Ming-Kun.,Li, Li.,Wang, Wei.,...&Zhang, Guo-Fan.(2025).Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas).ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY,297,12. |
| MLA | Wang, Shen-Tong,et al."Comparative transcriptomic analysis reveals a differential acid response mechanism between estuarine oyster (Crassostrea ariakensis) and Pacific oyster (Crassostrea gigas)".ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 297(2025):12. |
入库方式： OAI收割
来源：海洋研究所
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